Description

Adamantyl-1,2-Dioxetane Phosphate is a highly specialized chemiluminescent substrate used as a key reagent in sensitive detection assays. Its core value lies in generating a sustained, enzyme-amplified light signal, enabling the detection of extremely low analyte concentrations. This compound is essential for researchers and manufacturers in the life sciences, diagnostics, and pharmaceutical development sectors, particularly for applications in immunoassays, nucleic acid detection, and blotting techniques.

Application

• Chemiluminescent Substrate for Immunoassays: Used in ELISA, Western blotting, and other immunoassay formats to detect proteins and antibodies with high sensitivity and low background.
• Nucleic Acid Detection: Serves as a substrate for alkaline phosphatase-labeled probes in Southern, Northern, and dot/slot blotting for DNA and RNA analysis.
• Diagnostic Kit Manufacturing: A critical raw material in the production of clinical diagnostic kits for infectious diseases, hormones, and cancer markers.
• Research & Development: Employed in academic and industrial R&D for developing novel assay platforms and studying biomolecular interactions.
• High-Throughput Screening (HTS): Utilized in pharmaceutical discovery for screening compound libraries due to its stable light output and compatibility with automated systems.
• Biosensor Development: Integrated into biosensor designs as a signal-generating component for environmental monitoring or point-of-care testing devices.

Basic Information

Product Name	Adamantyl-1,2-Dioxetane Phosphate
CAS No.	144210-50-4
Molecular Formula	C12H19O6P
Molecular Weight	290.25 g/mol
Synonyms	AMPPD (3-(2'-Spiroadamantane)-4-methoxy-4-(3''-phosphoryloxy)phenyl-1,2-dioxetane); Disodium 3-(4-Methoxyspiro[1,2-dioxetane-3,2'-tricyclo[3.3.1.13,7]decan]-4-yl)phenyl Phosphate; CSPD® (Registered Trade Name); Chemiluminescent Alkaline Phosphatase Substrate; 1,2-Dioxetane Phosphate, Adamantyl-Substituted; Lumigen PPD; AP Substrate.
EINECS	Contact for details

Quality Control

Our Adamantyl-1,2-Dioxetane Phosphate is manufactured under strict quality systems to ensure batch-to-batch consistency and performance reliability for critical diagnostic and research applications. Each lot undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to meet stringent in-house specifications. A comprehensive Certificate of Analysis (COA) detailing purity, performance in standard assay systems, and stability data is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This compound is both light-sensitive (store away from light) and hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature before opening to minimize condensation and moisture uptake. For long-term stability, store desiccated at the recommended temperature.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Performance (Chemiluminescence)	Meets reference standard activity
Solubility	Soluble in DMSO, DMF; slightly soluble in water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.