Description

Rel-Associated Protein Pp40 CAS NO 144197-45-5 is a specialized biochemical reagent of significant interest in molecular biology and pharmaceutical research. This compound plays a crucial role in the study of cellular signaling pathways, particularly those involving the Rel/NF-κB transcription factor family, which is central to immune response, inflammation, and cell survival. It is an essential tool for researchers and developers in the fields of biopharmaceuticals, academic research, and diagnostic assay development who require high-purity, reliable reagents for critical experiments and process development.

Application

• Biochemical Research: Used as a key reagent in studying protein-protein interactions, signal transduction mechanisms, and the regulation of gene expression related to immune and inflammatory responses.
• Drug Discovery & Development: Serves as a target or tool compound in high-throughput screening (HTS) assays to identify and validate novel therapeutic agents for cancer, autoimmune diseases, and chronic inflammation.
• Diagnostic Kit Manufacturing: Employed in the development and production of enzyme-linked immunosorbent assays (ELISA) and other immunoassays for research and clinical diagnostics.
• Academic & Institutional Laboratories: Essential for fundamental research in cell biology, immunology, and oncology within university and government research institutes.
• Biopharmaceutical Production: May be utilized in process development and quality control for biologics where understanding and controlling specific cellular pathways is critical.

Basic Information

Product Name	Rel-Associated Protein Pp40
CAS No.	144197-45-5
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Pp40; Rel-associated protein; RelA-associated protein p40; NF-κB p40 subunit; IκB-like protein; NFKB p40; RelA binding protein; Signal transduction protein p40
EINECS	Contact for details

Quality Control

Every batch of Rel-Associated Protein Pp40 is manufactured and tested under stringent quality management systems to ensure the highest standards of purity and biological activity. Our products undergo rigorous quality testing, including advanced analytical techniques, to ensure compliance with industry standards for research-grade biochemicals. Certificates of Analysis (COA) detailing purity, identity, and functional activity are available upon request to support your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below for long-term stability. This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to minimize exposure to atmospheric moisture. For short-term use, aliquots may be stored at 2-8°C.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Protein Content (BCA)	≥ 90%
Biological Activity (Functional Assay)	Reported per batch
Endotoxin Level (LAL)	< 1.0 EU/μg
Solubility	Soluble in appropriate aqueous buffers

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.