Description

Ribosome-Inactivating Protein, Maize is a potent, naturally occurring protein that catalytically inactivates eukaryotic ribosomes, halting protein synthesis. This specific activity makes it a critical research tool for studying protein synthesis mechanisms, cell biology, and for the development of targeted immunotoxins. It is primarily utilized by researchers and developers in the life sciences, pharmaceutical R&D, and biotechnology sectors for applications ranging from fundamental biochemical studies to novel therapeutic agent design.

Application

• Biomedical Research: Fundamental studies on ribosome function, protein synthesis inhibition, and apoptosis.
• Immunotoxin Conjugate Development: As the toxic payload in antibody-drug conjugates (ADCs) for targeted cancer therapy research.
• Cell Biology Studies: Tool for selectively ablating specific cell populations or studying stress responses in eukaryotic cells.
• Virology Research: Investigation of antiviral mechanisms and host-pathogen interactions at the translational level.
• Plant Biochemistry: Study of plant defense mechanisms and the role of RIPs in plant physiology.
• Diagnostic Reagent Component: Potential use in diagnostic assays requiring specific inhibition of cellular processes.

Basic Information

Product Name	Ribosome-Inactivating Protein, Maize
CAS No.	144132-05-8
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Maize RIP; Maize Ribosome-Inactivating Protein; Zea mays Ribosome-Inactivating Protein; RIP from Maize; Type 1 Ribosome-Inactivating Protein; b-32 Protein; 30 kDa Ribosome-Inactivating Protein; Protein Synthesis Inhibitor from Maize
EINECS	Contact for details

Quality Control

Our Ribosome-Inactivating Protein, Maize is produced and tested under stringent conditions to ensure high purity, consistent activity, and batch-to-batch reproducibility. Quality is verified through a battery of analytical techniques including SDS-PAGE, HPLC, and functional activity assays. A comprehensive Certificate of Analysis (COA) detailing purity, biological activity, and endotoxin levels is provided with each batch to support your research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below. This product is hygroscopic (moisture-sensitive); allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (SDS-PAGE)	Single major band (~30 kDa)
Purity (HPLC)	≥ 95%
Protein Content (Bradford)	≥ 90%
Biological Activity (Cell-free assay)	IC50 provided on COA
Endotoxin Level (LAL)	< 1.0 EU/µg
Solubility	Soluble in aqueous buffers

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.