Description

3-[Bis(4-Fluorophenyl)Phosphinyl]Benzenamine is a high-value organophosphorus compound featuring a phosphinyl bridge and fluorinated aromatic rings, serving as a critical advanced intermediate in modern synthetic chemistry. Its precise molecular architecture makes it indispensable for constructing complex molecules where specific electronic and steric properties are required. This compound is primarily sought by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly in kinase inhibitor and central nervous system (CNS) active compound research.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and plant growth regulators that require fluorinated phosphinyl motifs for enhanced activity and stability.
• Ligand Precursor: Serves as a precursor for sophisticated phosphine-based ligands used in transition metal catalysis, enabling challenging cross-coupling and asymmetric reactions.
• Material Science Research: Investigated for incorporation into specialty polymers, flame retardants, and electronic materials to impart specific thermal and electronic properties.
• Chemical Research & Development: A versatile reagent for academic and industrial R&D exploring new reaction methodologies and the creation of complex molecular libraries.

Basic Information

Product Name	3-[Bis(4-Fluorophenyl)Phosphinyl]Benzenamine
CAS No.	144091-76-9
Molecular Formula	C18H14F2NOP
Molecular Weight	329.28 g/mol
Synonyms	3-Aminophenylbis(4-fluorophenyl)phosphine oxide; Benzenamine, 3-[bis(4-fluorophenyl)phosphinyl]-; [3-Aminophenyl]bis(4-fluorophenyl)phosphine oxide; 3-(Bis(4-fluorophenyl)phosphoryl)aniline; N-(3-Phosphinylphenyl)bis(4-fluorophenyl)amine (incorrect but common search variant); Phosphine oxide, (3-aminophenyl)bis(4-fluorophenyl)-; 144091-76-9 (CAS name-based synonym)
EINECS	Contact for details

Quality Control

Every batch of 3-[Bis(4-Fluorophenyl)Phosphinyl]Benzenamine is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for advanced synthetic applications. A detailed Certificate of Analysis (COA), including results for identity, purity, and impurity profile (typically by HPLC), is supplied with each shipment to guarantee consistent quality and traceability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.