Description

n-(tert-Butyl)-2-Chloronicotinamide is a specialized organic intermediate featuring a nicotinamide core structure substituted with a tert-butyl group and a chlorine atom. This compound is valued for its role as a versatile building block in the synthesis of more complex molecules, particularly in advanced pharmaceutical and agrochemical research. It is primarily sought by R&D chemists and process development scientists in the fine chemical, pharmaceutical, and crop protection industries for constructing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in kinase inhibitor and other targeted therapeutic research.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, leveraging its chloronicotinamide scaffold.
• Chemical Research & Development: Serves as a versatile precursor for creating custom ligands, catalysts, and functionalized organic compounds in academic and industrial labs.
• Material Science: Potential intermediate in the synthesis of specialty polymers or organic electronic materials due to its aromatic and amide functionalities.

Basic Information

Product Name	n-(tert-Butyl)-2-Chloronicotinamide
CAS No.	144084-34-4
Molecular Formula	C10H13ClN2O
Molecular Weight	212.68 g/mol
Synonyms	2-Chloro-N-(tert-butyl)nicotinamide; N-tert-Butyl-2-chloronicotinamide; 2-Chloro-N-(1,1-dimethylethyl)-3-pyridinecarboxamide; 2-Chloronicotinic acid tert-butylamide; tert-Butyl 2-chloronicotinamide; 144084-34-4; 2-Chloro-N-tert-butylnicotinamide
EINECS	Contact for details

Quality Control

Our n-(tert-Butyl)-2-Chloronicotinamide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for research and development applications. A detailed Certificate of Analysis (COA) is provided with every shipment to guarantee traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.