Description

1-(Dimethoxymethyl)-2,4-Difluorobenzene is a high-purity fluorinated aromatic building block of significant importance in advanced organic synthesis. Its unique structure, featuring a protected aldehyde group and fluorine substituents, makes it a versatile precursor for constructing complex molecules. This compound is primarily sought after by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of active ingredients and novel chemical entities.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring difluorobenzene or benzaldehyde derivatives.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides where the fluorine atoms enhance biological activity and metabolic stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in catalysis and material science applications.
• Organic Electronic Materials: A potential building block for fluorinated organic semiconductors and charge-transport materials.
• Custom Synthesis and Contract Manufacturing: Supplied to CROs and CMOs for use in client-specific discovery and scale-up projects.
• Academic and Industrial R&D: Employed in research laboratories for method development and exploring new chemical spaces in medicinal and synthetic chemistry.

Basic Information

Product Name	1-(Dimethoxymethyl)-2,4-Difluorobenzene
CAS No.	144062-35-1
Molecular Formula	C9H10F2O2
Molecular Weight	188.17 g/mol
Synonyms	2,4-Difluorobenzaldehyde dimethyl acetal; (2,4-Difluorophenyl)(dimethoxy)methane; α,α-Dimethoxy-2,4-difluorotoluene; 2,4-Difluoro-α,α-dimethoxytoluene; 1-(Dimethoxymethyl)-2,4-difluorobenzene; Benzene, 1-(dimethoxymethyl)-2,4-difluoro-; 2,4-Difluorobenzaldehyde dimethylacetal
EINECS	Contact for details

Quality Control

Our 1-(Dimethoxymethyl)-2,4-Difluorobenzene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment ensures material consistency and reliability for your critical R&D and production processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Purity (by GC/HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%
Related Substances (by GC/HPLC)	Individual impurity ≤ 1.0%; Total impurities ≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.