Description

2,4-Difluorophenylboronic Acid is a high-purity organoboron compound, serving as a critical building block in modern synthetic chemistry. Its value lies in enabling efficient carbon-carbon bond formation via Suzuki-Miyaura cross-coupling reactions, a cornerstone of pharmaceutical and advanced materials development. This reagent is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries seeking to synthesize complex fluorinated aromatic structures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those containing difluorophenyl motifs for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in creating novel herbicides, fungicides, and insecticides where the difluorophenyl group contributes to biological activity and environmental persistence.
• Liquid Crystal & OLED Materials: Employed in the production of fluorinated aromatic components for advanced electronic displays and organic light-emitting diodes (OLEDs).
• Polymer & Resin Modification: Acts as a monomer or cross-linking agent in the development of specialty polymers with tailored thermal and chemical resistance properties.
• Chemical Research & Development: A versatile reagent in academic and industrial R&D labs for constructing complex molecular architectures in medicinal chemistry and material science projects.
• Ligand Synthesis for Catalysis: Serves as a starting material for synthesizing sophisticated boron-containing ligands used in asymmetric catalysis.

Basic Information

Product Name	2,4-Difluorophenylboronic Acid
CAS No.	144025-03-6
Molecular Formula	C6H5BF2O2
Molecular Weight	157.91 g/mol
Synonyms	(2,4-Difluorophenyl)boronic Acid; 2,4-Difluorobenzeneboronic Acid; B-(2,4-Difluorophenyl)boronic Acid; 2,4-DFPBA; 144025-03-6; 2,4-Difluorophenyl-B(OH)2; Boronic acid, B-(2,4-difluorophenyl)-
EINECS	Contact for details

Quality Control

Our 2,4-Difluorophenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and consistency. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Assay (Titration)	95.0 - 102.0%
Water Content (KF)	≤ 1.0%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.