Description

Tyrosyl-Prolyl-Psi(Methylamino)Phenylalanyl-Prolyl-Glycine is a synthetic peptide of significant interest in advanced biomedical research and development. Its unique structure, incorporating a psi (ψ) pseudopeptide bond, makes it a valuable tool for studying enzyme inhibition and receptor-ligand interactions. This compound is primarily utilized by pharmaceutical R&D teams and academic institutions focused on peptide-based therapeutics and biochemical pathway analysis. Its precise molecular architecture is critical for applications requiring high specificity and biological activity.

Application

• Pharmaceutical Research & Development: Serves as a key intermediate or reference standard in the discovery of novel peptide-based drugs and therapeutic agents.
• Biochemical Assay Development: Used as a substrate or inhibitor in enzymatic studies to investigate protease activity and specificity.
• Proteomics and Signal Transduction Research: Employed to probe protein-protein interactions and cellular signaling pathways that are relevant to disease mechanisms.
• Academic and Institutional Research: A critical reagent for universities and research institutes conducting fundamental studies in peptide chemistry and medicinal biology.
• High-Throughput Screening (HTS): Integrated into compound libraries for screening campaigns aimed at identifying new bioactive molecules.
• Reference Material Production: Used by manufacturers to produce certified reference standards for quality control in peptide synthesis.

Basic Information

Item	Details
Product Name	Tyrosyl-Prolyl-Psi(Methylamino)Phenylalanyl-Prolyl-Glycine
CAS No.	143984-57-0
Molecular Formula	C38H49N7O8
Molecular Weight	731.85 g/mol
Synonyms	Y-P-ψ[CH2NH]-F-P-G; Tyr-Pro-ψ[CH2NH]-Phe-Pro-Gly; Pseudopeptide Inhibitor; Reduced Peptide Bond Inhibitor; TPPFG; CAS 143984-57-0; Tyrosyl-prolyl-(N-methyl)phenylalanyl-prolyl-glycine (pseudopeptide)
EINECS	Contact for details

Quality Control

Our Tyrosyl-Prolyl-Psi(Methylamino)Phenylalanyl-Prolyl-Glycine is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including HPLC for purity and MS for identity confirmation, to ensure it meets the high standards required for research applications. Certificates of Analysis (COA) detailing all test results are available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Peptide Content	≥ 80.0%
Single Impurity (HPLC)	≤ 2.0%
Solubility	Soluble in DMSO, DMF; sparingly soluble in water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.