Description

S100 Alpha Protein, Human is a highly purified, biologically active protein complex belonging to the S100 family of calcium-binding proteins. This product is critical for advanced biomedical research and diagnostic development, offering a reliable standard for studying inflammatory responses, cellular signaling, and disease mechanisms. It is essential for researchers and manufacturers in the fields of immunology, neurology, and oncology, as well as for the production of high-sensitivity diagnostic assays.

Application

• Biomedical Research: Used as a key reagent in studying the role of S100 proteins in inflammation, cell proliferation, and apoptosis.
• Diagnostic Kit Development: Serves as a critical antigen or standard for calibrating immunoassays (ELISA, CLIA) targeting biomarkers like S100A1, S100B, or S100A8/A9.
• Drug Discovery & Target Validation: Employed in high-throughput screening (HTS) and functional assays to identify and validate novel therapeutic compounds.
• Clinical Studies: Utilized as a reference material in correlating protein expression levels with clinical outcomes in neurological disorders, cardiovascular diseases, and cancers.
• Quality Control & Standardization: Acts as a primary standard for the quality control of in-house produced proteins or commercial diagnostic reagents.

Basic Information

Product Name	S100 Alpha Protein, Human
CAS No.	143923-34-6
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	S100 Protein; S100 Calcium-Binding Protein A1; S100A1; S100 Alpha Chain; Calcyclin; S100 Calcium Binding Protein A1 (Human); S100A Protein; MRP-8/14 Complex (S100A8/A9); Calgranulin A/B
EINECS	Contact for details

Quality Control

Our S100 Alpha Protein, Human is produced under stringent conditions to ensure batch-to-batch consistency and biological activity. Each lot undergoes rigorous analytical testing, including purity assessment by HPLC and SDS-PAGE, identity confirmation, and functional activity assays. A comprehensive Certificate of Analysis (COA) detailing purity, endotoxin levels, and biological activity is provided with every shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive). For long-term storage, aliquot to avoid repeated freeze-thaw cycles and store under recommended conditions.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to standard
Purity (SDS-PAGE)	≥ 95%
Protein Content (BCA)	≥ 90%
Endotoxin Level (LAL)	< 1.0 EU/µg
Biological Activity (Cell-based assay)	Contact for details
Solubility	Soluble in aqueous buffers

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.