Description

D-Valine, n-(1-Oxobutyl)- (9Ci) is a chiral, non-proteinogenic amino acid derivative characterized by its specific D-configuration and butyryl side chain. This compound is a critical building block in advanced organic synthesis and pharmaceutical research, where precise stereochemistry is paramount. It is primarily utilized by researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for applications such as peptide synthesis and the development of chiral catalysts.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel active pharmaceutical ingredients (APIs), particularly for drugs targeting neurological and metabolic disorders.
• Peptide Synthesis: Used in solid-phase and solution-phase peptide synthesis to incorporate D-amino acids, which can enhance the metabolic stability and bioavailability of therapeutic peptides.
• Agrochemical Research: Serves as a precursor in the synthesis of chiral herbicides, fungicides, and plant growth regulators, where the D-configuration can influence biological activity.
• Biochemical Research: Employed in enzymatic studies and as a substrate analog to investigate enzyme specificity and inhibition mechanisms.
• Chiral Catalyst & Ligand Development: Acts as a starting material for synthesizing sophisticated chiral ligands and organocatalysts used in asymmetric synthesis.
• Reference Standard: Used as a high-purity analytical standard in quality control laboratories for method development and validation in chiral analysis.

Basic Information

Item	Detail
Product Name	D-Valine, n-(1-Oxobutyl)- (9Ci)
CAS No.	143896-77-9
Molecular Formula	C9H17NO3
Molecular Weight	187.24 g/mol
Synonyms	N-Butyryl-D-valine; D-2-Amino-3-methylbutanoic acid butyramide; (R)-2-Amino-3-methyl-N-(1-oxobutyl)butanamide; Butanamide, N-[(1R)-2-amino-1-(1-methylethyl)ethyl]-; D-Valine butyramide; N-Butanoyl-D-valine
EINECS	Contact for details

Quality Control

Our D-Valine, n-(1-Oxobutyl)- (9Ci) is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including chiral purity assessment by HPLC, to ensure it meets the high standards required for research and development. A Certificate of Analysis (COA) detailing identity, purity, and specific impurities is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a desiccated environment to maintain stability and purity. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.