Description

(S)-4-Benzyl-3-Pentanoyloxazolidin-2-One CAS NO 143868-89-7 is a high-purity chiral auxiliary and synthetic intermediate of significant importance in asymmetric organic synthesis. Its primary value lies in enabling the stereoselective construction of complex molecules, ensuring high enantiomeric excess in the final products. This compound is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries who require reliable and consistent building blocks for advanced synthesis.

Application

• Asymmetric Synthesis: As a versatile Evans-type chiral auxiliary for the diastereoselective alkylation, aldol, and Michael addition reactions.
• Pharmaceutical Intermediates: Key building block in the synthesis of active pharmaceutical ingredients (APIs) requiring specific stereochemistry.
• Agrochemical Development: Used in the research and production of chiral pesticides and herbicides.
• Fine Chemical Manufacturing: Intermediate for producing specialty chemicals, flavors, and fragrances where stereochemical purity is critical.
• Academic & Industrial R&D: A standard reagent in method development and catalysis studies within organic chemistry laboratories.
• Process Chemistry: Employed in scale-up and optimization of synthetic routes for cost-effective manufacturing of chiral compounds.

Basic Information

Product Name	(S)-4-Benzyl-3-Pentanoyloxazolidin-2-One
CAS No.	143868-89-7
Molecular Formula	C15H19NO3
Molecular Weight	261.32 g/mol
Synonyms	(S)-4-Benzyl-3-valeryl-2-oxazolidinone; (S)-4-Benzyl-3-(pentanoyl)-2-oxazolidinone; (S)-(-)-4-Benzyl-3-pentanoyl-2-oxazolidinone; Evans Auxiliary (S)-Valeryl; (S)-N-Pentanoyl-4-benzyl-2-oxazolidinone; (S)-4-Benzyl-3-(1-oxopentyl)-2-oxazolidinone; (S)-N-Valeryl-4-benzyl-2-oxazolidinone
EINECS	Contact for details

Quality Control

Our (S)-4-Benzyl-3-Pentanoyloxazolidin-2-One is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral HPLC for enantiomeric purity and standard spectroscopic methods for identity confirmation, to ensure it meets the high standards required for synthetic applications. Certificates of Analysis (COA) documenting purity, chiral purity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Melting Point	Contact for details
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.