Description

Protein E7(43-62) CAS NO 143853-58-1 is a synthetic peptide fragment derived from the E7 oncoprotein of human papillomavirus (HPV). This high-purity peptide is a critical research tool for immunological studies and vaccine development, offering precise molecular targeting. It is primarily utilized by researchers and developers in the fields of oncology, virology, and immunology for epitope mapping, antibody production, and as a reference standard in diagnostic assay development.

Application

• Immunological Research: Used as a defined antigen for studying T-cell and B-cell immune responses to HPV infection.
• Vaccine Development: Serves as a key component in the research and preclinical testing of peptide-based vaccines targeting HPV-associated cancers.
• Diagnostic Reagent: Acts as a coating antigen or reference standard in ELISA and other immunoassays for detecting HPV-specific antibodies.
• Epitope Mapping: Essential for identifying and characterizing specific antigenic determinants within the HPV E7 protein.
• Antibody Production: Employed to generate and purify monoclonal or polyclonal antibodies with specificity for the E7(43-62) region.
• Biomarker Studies: Used in research investigating the role of specific HPV epitopes in disease progression and as potential biomarkers.

Basic Information

Product Name	Protein E7(43-62)
CAS No.	143853-58-1
Molecular Formula	C96H155N29O27S
Molecular Weight	2155.5 g/mol
Synonyms	HPV-16 E7 Protein (43-62); HPV16 E7 (43-62); E7 Oncoprotein Fragment (43-62); LYCYEQLNDSSEEEDEIDGPAG; Human Papillomavirus Type 16 E7 Peptide (43-62); HPV E7 Antigenic Peptide; E7(43-62) peptide
EINECS	Contact for details

Quality Control

Every batch of Protein E7(43-62) is manufactured and analyzed under stringent quality management systems. Our products undergo rigorous purity and identity verification using advanced analytical techniques including HPLC and mass spectrometry to ensure compliance with research-grade standards. A comprehensive Certificate of Analysis (COA) detailing purity, peptide content, and analytical data is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store desiccated at -20°C or below. This product is hygroscopic (moisture-sensitive) and easily oxidized; it is recommended to store under an inert atmosphere when the container is opened frequently. Allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC & MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Peptide Content	≥ 70%
Amino Acid Composition	Conforms to theoretical values (±10%)
Molecular Weight	2155.5 ± 2.0 Da (MALDI-TOF or ESI-MS)
Solubility	Soluble in water or dilute acetic acid
Single Impurity (HPLC)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.