Description

Herpesvirus 4 Ie Protein CAS NO 143844-99-9 is a highly purified recombinant protein derived from the immediate-early (IE) gene of Epstein-Barr virus (EBV), also known as Human Herpesvirus 4. This protein serves as a critical reagent for virology research, enabling the study of viral replication, latency, and host-cell interactions. It is essential for researchers and diagnostic developers in the fields of infectious disease research, vaccine development, and serological assay production.

Application

• Research Reagent: Used as a key antigen in fundamental virology studies to investigate EBV pathogenesis and the viral life cycle.
• Diagnostic Development: Serves as a critical coating antigen in ELISA (Enzyme-Linked Immunosorbent Assay) kits for the detection of EBV-specific antibodies (e.g., anti-EA, anti-VCA).
• Biomarker Discovery: Employed in proteomics and immunoprecipitation assays to identify host proteins that interact with the IE protein.
• Therapeutic Target Validation: Utilized in high-throughput screening (HTS) platforms to identify potential antiviral compounds that inhibit IE protein function.
• Quality Control Standard: Acts as a reference standard for the calibration and validation of diagnostic assays and research tools.

Basic Information

Item	Detail
Product Name	Herpesvirus 4 Ie Protein
CAS No.	143844-99-9
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Epstein-Barr Virus Immediate-Early Protein; EBV IE Protein; HHV-4 IE Protein; BZLF1 Protein (Zebra Protein); EB1 Protein; Zta Transactivator Protein; Recombinant EBV Antigen; EBV EA (Early Antigen) Protein.
EINECS	Contact for details

Quality Control

Our Herpesvirus 4 Ie Protein is produced under stringent conditions to ensure high purity, batch-to-batch consistency, and biological activity. Each lot undergoes comprehensive analytical testing, including SDS-PAGE, Western Blot, and endotoxin level assessment. Certificates of Analysis (COA) detailing purity, concentration, and functional data are provided with every shipment to support your regulatory and research requirements.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store lyophilized material at -20°C or below. Upon reconstitution, aliquot and store at -80°C to avoid repeated freeze-thaw cycles. The product is hygroscopic (moisture-sensitive); ensure it is equilibrated to room temperature before opening to prevent condensation.

Specification

Item	Specification
Appearance	White or off-white lyophilized powder
Purity (SDS-PAGE)	> 95%
Identification (Western Blot)	Positive reactivity with specific antisera
Protein Content (BCA)	> 90% of stated weight
Endotoxin Level (LAL)	< 1.0 EU/µg
Biological Activity (ELISA)	Functionally active as an antigen
Solubility	Soluble in PBS or appropriate aqueous buffer

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.