Description

4-(4,4-Dimethyl-2,5-Dioxoimidazolidin-1-Yl)-2-Trifluoromethylbenzonitrile is a high-value, specialized organic intermediate featuring a unique molecular architecture combining an imidazolidinedione core with a benzonitrile and trifluoromethyl group. This compound matters for its role as a critical building block in the synthesis of advanced pharmaceuticals and agrochemicals, where its structure imparts desirable biological activity and metabolic stability. It is primarily needed by research and development chemists, process development scientists, and manufacturers in the pharmaceutical, agrochemical, and advanced material sectors seeking to develop novel active ingredients.

Application

• Pharmaceutical Intermediate: Key synthon for the development of novel small-molecule drugs, particularly in therapeutic areas targeting enzymes or receptors where the imidazolidinedione moiety is pharmacologically relevant.
• Agrochemical Active Ingredient Synthesis: Serves as a precursor in the manufacture of advanced herbicides, fungicides, or insecticides, leveraging the trifluoromethyl group for enhanced lipophilicity and bioactivity.
• Chemical Research & Development: Used as a versatile scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Advanced Material Precursor: Potential building block for specialty polymers, liquid crystals, or organic electronic materials due to its rigid, conjugated structure and functional groups.
• Process Chemistry & Scale-Up: Employed in route scouting and optimization for the commercial production of target molecules containing this sophisticated heterocyclic fragment.

Basic Information

Product Name	4-(4,4-Dimethyl-2,5-Dioxoimidazolidin-1-Yl)-2-Trifluoromethylbenzonitrile
CAS No.	143782-20-1
Molecular Formula	C13H10F3N3O2
Molecular Weight	297.24 g/mol
Synonyms	1-[4-Cyano-3-(trifluoromethyl)phenyl]-4,4-dimethylimidazolidine-2,5-dione; 2-Trifluoromethyl-4-(4,4-dimethyl-2,5-dioxo-1-imidazolidinyl)benzonitrile; 4,4-Dimethyl-1-[4-cyano-3-(trifluoromethyl)phenyl]imidazolidine-2,5-dione; 4-(4,4-Dimethyl-2,5-dioxoimidazolidin-1-yl)-2-(trifluoromethyl)benzonitrile; 143782-20-1; 4,4-Dimethyl-1-(4-cyano-3-trifluoromethylphenyl)imidazolidine-2,5-dione
EINECS	Contact for details

Quality Control

Our 4-(4,4-Dimethyl-2,5-Dioxoimidazolidin-1-Yl)-2-Trifluoromethylbenzonitrile is produced under a strict quality management system. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets exacting specifications for research and production use. Certificates of Analysis (COA) detailing batch-specific results are available upon request, providing full traceability and compliance data.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.