Description

Rbp-Jkappa Protein CAS NO 143777-43-9 is a highly purified recombinant protein of significant interest in biochemical and pharmaceutical research. This protein plays a crucial role in the study of specific intracellular signaling pathways and protein-protein interactions. It is primarily utilized by research institutions, diagnostic developers, and biopharmaceutical companies engaged in advanced life science applications. The product is supplied with a commitment to high purity and batch-to-batch consistency to ensure reliable experimental results.

Application

• Biochemical Research: Used as a critical reagent in studies of transcription regulation, signal transduction, and cellular function.
• Drug Discovery & Development: Serves as a target protein for screening potential therapeutic compounds in high-throughput assays.
• Diagnostic Kit Development: Employed as a purified antigen or standard in the development of immunoassays and diagnostic tests.
• Protein-Protein Interaction Studies: Essential for pull-down assays, co-immunoprecipitation (Co-IP), and surface plasmon resonance (SPR) analysis.
• Antibody Production & Validation: Acts as an immunogen for generating specific antibodies or as a control for antibody specificity testing.
• Enzymology Studies: Utilized in functional assays to investigate enzymatic activity and kinetics.

Basic Information

Product Name	Rbp-Jkappa Protein
CAS No.	143777-43-9
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Recombination Signal Binding Protein For Immunoglobulin Kappa J Region; RBP-Jkappa; RBP-J(kappa); CBF1; Suppressor of Hairless; Su(H); Jkappa-Recombination Signal Binding Protein; CSL Protein; Notch Signaling Transcription Factor RBPJ
EINECS	Contact for details

Quality Control

Our Rbp-Jkappa Protein is produced under stringent quality management systems. Each batch is subjected to a comprehensive suite of analytical tests, including purity assessment by SDS-PAGE and HPLC, identity confirmation, and endotoxin level testing. Certificates of Analysis (COA) detailing all specifications and test results are provided to ensure full traceability and compliance with research-grade standards.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below. Avoid repeated freeze-thaw cycles. The product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent degradation.

Specification

Item	Specification
Appearance	White or off-white lyophilized powder
Identification (SDS-PAGE)	Single band at expected molecular weight
Purity (HPLC)	≥ 95%
Protein Content (BCA)	≥ 90%
Endotoxin Level (LAL)	< 1.0 EU/µg
Biological Activity	Confirmed by functional assay (e.g., DNA-binding ELISA)
Solubility	Soluble in appropriate aqueous buffers

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.