Description

C-Mpl Protein CAS NO 143641-95-6 is a recombinant human thrombopoietin receptor protein, a critical cytokine receptor involved in the regulation of megakaryocyte proliferation and platelet production. This high-purity protein is essential for advanced life science research and biopharmaceutical development, particularly in hematology and oncology. It is primarily utilized by research institutions, diagnostic kit manufacturers, and biotech companies engaged in drug discovery and cell signaling studies.

Application

• Biopharmaceutical Research & Development: Used as a key reagent in the study of thrombopoietin signaling pathways, hematopoiesis, and myeloproliferative disorders.
• Drug Discovery & Screening: Serves as a target protein in high-throughput screening (HTS) assays for identifying novel therapeutic agents targeting platelet disorders.
• Diagnostic Development: Employed as a critical component in the development of immunoassays and diagnostic kits for measuring thrombopoietin levels or receptor activity.
• Cell Culture & Differentiation Studies: Used to support the in vitro expansion and differentiation of megakaryocytic progenitor cells in stem cell research.
• Protein-Protein Interaction Studies: A vital tool for investigating binding kinetics and interactions with ligands and other signaling molecules.
• Reference Standard: Functions as a qualified reference standard for quality control and assay calibration in regulated bioanalytical laboratories.

Basic Information

Product Name	C-Mpl Protein
CAS No.	143641-95-6
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Thrombopoietin Receptor; TPO-R; Myeloproliferative Leukemia Virus Oncogene; CD110; MPLV; C-MPL; TPOR; MPL Proto-Oncogene, Thrombopoietin Receptor
EINECS	Contact for details

Quality Control

Our C-Mpl Protein is manufactured under stringent quality systems. Each batch undergoes comprehensive analytical testing, including purity assessment by HPLC, identity confirmation, and bioactivity assays to ensure consistency and performance. A detailed Certificate of Analysis (COA), providing batch-specific data, is supplied with every order to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below for long-term stability. This product is hygroscopic (moisture-sensitive). Aliquot to avoid repeated freeze-thaw cycles. Handle under appropriate conditions to maintain protein integrity.

Specification

Item	Specification
Appearance	White or off-white lyophilized powder
Identification (SDS-PAGE)	Corresponds to standard
Purity (HPLC)	≥ 95%
Endotoxin Level (LAL)	< 1.0 EU/µg
Bioactivity (Cell-based assay)	Meets defined activity range
Solubility	Soluble in appropriate aqueous buffers

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.