Description

3-Fluoro-4-Methoxymethoxyphenylboronic Acid is a specialized organoboron compound that serves as a crucial building block in modern synthetic chemistry. Its value lies in its dual functionality, where the boronic acid group enables efficient cross-coupling reactions, and the fluorine and methoxymethoxy substituents provide unique electronic and steric properties for fine-tuning molecular structures. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries developing novel active ingredients, particularly in the synthesis of complex heterocycles and functionalized aromatic systems.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for constructing biaryl scaffolds found in drug candidates.
• Agrochemical Synthesis: Used in the development of advanced herbicides and fungicides that require specific fluorinated aromatic motifs.
• Material Science Research: Serves as a monomer or functionalization agent in the creation of novel organic electronic materials and liquid crystals.
• Chemical Biology Probes: Employed in the synthesis of fluorophore-labeled compounds or activity-based probes for biological target identification.
• Catalyst Ligand Development: The unique substitution pattern makes it a valuable starting material for synthesizing novel ligands for transition metal catalysis.
• Custom Synthesis & Contract Manufacturing: A critical raw material for fine chemical companies offering bespoke synthesis services for clients in R&D.

Basic Information

Product Name	3-Fluoro-4-Methoxymethoxyphenylboronic Acid
CAS No.	143610-62-2
Molecular Formula	C9H12BFO4
Molecular Weight	214.00 g/mol
Synonyms	(3-Fluoro-4-(methoxymethoxy)phenyl)boronic acid; 3-Fluoro-4-(methoxymethoxy)benzeneboronic acid; B-[3-Fluoro-4-(methoxymethoxy)phenyl]boronic acid; 3-Fluoro-4-methoxymethoxybenzeneboronic acid; (3-Fluoro-4-methoxymethoxyphenyl)boronic Acid; 4-Methoxymethoxy-3-fluorophenylboronic acid
EINECS	Contact for details

Quality Control

Our 3-Fluoro-4-Methoxymethoxyphenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and elemental analysis, to ensure high chemical purity and consistent performance in sensitive coupling reactions. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.