Description

4-Morpholineacetamide, n-(2-Fluorophenyl)-, Monohydrochloride is a high-purity, fluorinated organic compound that serves as a critical building block in advanced pharmaceutical synthesis. This compound is valued for its role as a versatile intermediate, enabling the development of novel active pharmaceutical ingredients (APIs) with targeted biological activity. It is primarily required by research institutions and pharmaceutical manufacturers engaged in the development of new therapeutic agents, particularly in areas requiring complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and production of new drug candidates, especially those targeting central nervous system (CNS) disorders.
• Active Pharmaceutical Ingredient (API) Development: Used in the synthesis of complex molecules where the morpholine and fluorophenyl moieties are essential for biological activity and pharmacokinetic properties.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies to optimize lead compounds for potency and selectivity.
• Process Chemistry & Scale-Up: Serves as a standardized building block for the efficient, multi-kilogram scale synthesis of target molecules under Good Manufacturing Practice (GMP) conditions.
• Reference Standard: Can be supplied as a high-purity standard for analytical method development, validation, and quality control in pharmaceutical laboratories.

Basic Information

Product Name	4-Morpholineacetamide, n-(2-Fluorophenyl)-, Monohydrochloride
CAS No.	143579-16-2
Molecular Formula	C12H15FN2O2·HCl
Molecular Weight	274.72 g/mol
Synonyms	N-(2-Fluorophenyl)-4-morpholineacetamide hydrochloride; 2-Fluoro-N-(morpholin-4-ylacetyl)aniline hydrochloride; 4-Morpholineacetic acid, 2-fluoroanilide, hydrochloride; 4-(2-Fluorophenylcarbamoylmethyl)morpholine hydrochloride; (2-Fluorophenyl)(morpholinoacetyl)amine hydrochloride
EINECS	Contact for details

Quality Control

Our 4-Morpholineacetamide, n-(2-Fluorophenyl)-, Monohydrochloride is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for pharmaceutical research. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing purity, identity, and impurity profiles. Our quality commitment aligns with the standards expected for advanced chemical intermediates in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.