Description

Neurotrophin 4 is a high-purity recombinant protein belonging to the neurotrophin family, essential for the development and maintenance of the nervous system. This compound is critical for researchers and developers in the life sciences sector, offering a reliable tool for studying neuronal survival, differentiation, and synaptic plasticity. It is primarily utilized by biotechnology firms, academic research institutions, and pharmaceutical companies engaged in neuroscience research and therapeutic development for neurological disorders.

Application

• Neuroscience Research: Fundamental studies on neuronal cell survival, axon guidance, and synapse formation.
• Drug Discovery & Development: Screening and validation of novel therapeutic candidates targeting neurotrophic pathways.
• Cell Culture & Differentiation: A key component in media formulations for the maintenance and directed differentiation of neural stem cells.
• Disease Modeling: Used in in vitro models to investigate mechanisms of neurodegenerative diseases like Parkinson's and Alzheimer's.
• Biomanufacturing Support: Serves as a critical raw material or reference standard in the production of biologics and advanced therapy medicinal products (ATMPs).
• Regenerative Medicine: Investigated for its potential in nerve repair and regeneration strategies within tissue engineering.

Basic Information

Product Name	Neurotrophin 4
CAS No.	143551-63-7
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	NT-4; Neurotrophin-4; NT4/5; Neurotrophic Factor 4; NT-4/5; Neuritin-2; Recombinant Human Neurotrophin-4; rhNT-4
EINECS	Contact for details

Quality Control

Our Neurotrophin 4 is manufactured under stringent quality systems. Each batch undergoes comprehensive analytical testing, including identity confirmation, purity assessment, and bioactivity assays, to ensure it meets the exacting standards required for research and development. Certificates of Analysis (COA) detailing purity, endotoxin levels, and biological activity are provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store lyophilized material at -20°C or below. Reconstituted solutions should be aliquoted and stored at -80°C to avoid repeated freeze-thaw cycles. The product is hygroscopic (moisture-sensitive); ensure containers are sealed under inert atmosphere or desiccant when not in use.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (SDS-PAGE)	Complies
Purity (HPLC)	≥ 95%
Endotoxin Level (LAL)	< 1.0 EU/µg
Biological Activity (Cell-based assay)	Fully active
Solubility	Soluble in sterile PBS or cell culture grade water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.