Description

Dlg Protein, Drosophila is a recombinant protein derived from the Discs Large (Dlg) gene of *Drosophila melanogaster*, a key component in cellular signaling and structural organization. This high-purity protein is essential for fundamental research into cell polarity, synaptic scaffolding, and tumor suppressor mechanisms. It is a critical reagent for molecular biologists, biochemists, and pharmaceutical researchers focused on neurobiology, cell adhesion, and cancer pathways. CAS No. 143513-41-1.

Application

• Biochemical Research: Used as a standard or substrate in studies of PDZ domain interactions, MAGUK protein family function, and cell junction assembly.
• Drug Discovery Screening: Employed in in vitro assays to identify and characterize small molecules or biologics that modulate protein-protein interactions critical for cell signaling.
• Antibody Production & Validation: Serves as a high-quality immunogen for generating specific monoclonal or polyclonal antibodies against Dlg epitopes.
• Diagnostic Development: Potential use as a reference material in the development of diagnostic tests for conditions linked to cell polarity and adhesion defects.
• Academic & Institutional Research: Fundamental tool for investigating the role of scaffolding proteins in neurodevelopment, epithelial integrity, and tumor suppression models.
• Protein Interaction Mapping: Utilized in pull-down assays, co-immunoprecipitation, and surface plasmon resonance (SPR) to map binding partners and affinity.

Basic Information

Item	Details
Product Name	Dlg Protein, Drosophila
CAS No.	143513-41-1
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Discs Large Homolog 1 Protein (Drosophila); Dlg1; SAP97; hDlg; Synapse-Associated Protein 97; Disks Large Homolog 1; PSD-95/SAP90 Family Protein; MAGUK Protein p55; Recombinant Drosophila Dlg Protein
EINECS	Contact for details

Quality Control

Our Dlg Protein, Drosophila is produced under stringent conditions to ensure high purity, batch-to-batch consistency, and biological activity. Each lot undergoes comprehensive analytical testing, including SDS-PAGE, Western Blot, and functional activity assays. Certificates of Analysis (COA) detailing purity, concentration, endotoxin levels, and storage buffer are available upon request.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C to -80°C in aliquots to avoid repeated freeze-thaw cycles. The product is hygroscopic (moisture-sensitive); ensure containers are sealed tightly after use. Handle under appropriate laboratory conditions.

Specification

Item	Specification
Appearance	Clear to slightly opalescent solution
Purity (SDS-PAGE)	≥ 90%
Concentration	As per COA (typically 0.1-1.0 mg/mL)
Buffer Composition	Tris, NaCl, Glycerol, DTT (or similar stabilizing buffer)
Endotoxin Level	< 1.0 EU/μg
Biological Activity	Confirmed by functional assay (e.g., binding assay)
Identification (Western Blot)	Positive for expected molecular weight and specific antibody

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.