Description

H-Arg-Arg-Arg-Arg-Arg-Arg-Arg-Arg-Arg-Oh CAS NO 143413-47-2 is a synthetic nonapeptide composed of nine consecutive arginine residues, known for its high positive charge density and cell-penetrating properties. This compound is critical for advanced research and development in life sciences, particularly for studying intracellular delivery mechanisms and protein-protein interactions. It is primarily utilized by pharmaceutical R&D teams, academic research institutions, and biotechnology companies focused on novel drug delivery platforms and diagnostic tools.

Application

• Cell-Penetrating Peptide (CPP) Research: As a model cationic peptide for studying the mechanisms of cellular uptake and membrane translocation.
• Drug Delivery Vector: For the design and development of non-viral delivery systems for oligonucleotides, proteins, and other therapeutic cargoes.
• Bioconjugation & Labeling: Serves as a highly basic linker or tag for modifying biomolecules to alter their solubility or cellular targeting.
• Biomaterial & Surface Coating: Used to create positively charged surfaces for promoting cell adhesion in tissue engineering applications.
• Biochemical Tool: As a substrate or inhibitor in enzymatic assays studying processes like proteolysis or kinase activity.
• Antimicrobial Peptide (AMP) Studies: Investigated for its potential membrane-disruptive activity against pathogens due to its polycationic nature.

Basic Information

Item	Details
Product Name	H-Arg-Arg-Arg-Arg-Arg-Arg-Arg-Arg-Arg-Oh
CAS No.	143413-47-2
Molecular Formula	C54H110N36O10
Molecular Weight	1287.66 g/mol
Synonyms	Nonarginine; Polyarginine (n=9); Arg9; R9 Peptide; H-Arg9-OH; L-Arginine Nonamer; Nona-L-arginine; Cell-Penetrating Peptide R9
EINECS	Contact for details

Quality Control

Our H-Arg-Arg-Arg-Arg-Arg-Arg-Arg-Arg-Arg-Oh is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity, mass spectrometry (MS) for identity confirmation, and amino acid analysis (AAA). We provide a comprehensive Certificate of Analysis (COA) with each shipment, detailing all specifications and test results to ensure traceability and compliance with your research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This material is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC-MS)	Conforms
Purity (HPLC)	≥ 95%
Amino Acid Composition	Conforms to theoretical values
Water Content (KF)	≤ 5.0%
Peptide Content	≥ 80%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.