Description

Sodium 7-[[1-(3-Bromophenyl)Cyclopentanecarbonyl]Amino]-3-Methyl-8-Oxo -5-Thia-1-Azabicyclo[4.2.0]Oct-2-Ene-2-Carboxylate is a high-purity, advanced pharmaceutical intermediate with the CAS registry number 143407-74-3. This compound is a key synthon in the synthesis of novel cephalosporin antibiotics, offering researchers and manufacturers a critical building block for developing next-generation antimicrobial agents. It is primarily utilized by pharmaceutical R&D laboratories and active pharmaceutical ingredient (API) producers focused on anti-infective drug development.

Application

• Pharmaceutical Intermediate: A crucial precursor in the multi-step synthesis of advanced cephalosporin-class antibiotics.
• Antibiotic Research & Development: Serves as a core scaffold for medicinal chemists exploring new antibacterial compounds with improved efficacy and spectrum of activity.
• Active Pharmaceutical Ingredient (API) Manufacturing: Used in the controlled production of bulk antibiotic APIs under current Good Manufacturing Practice (cGMP) standards.
• Process Chemistry & Scale-Up: Enables optimization and scaling of synthetic routes from laboratory to pilot plant and commercial production.
• Reference Standard: Can be supplied as a high-purity analytical standard for quality control and method validation in pharmaceutical analysis.

Basic Information

Item	Detail
Product Name	Sodium 7-[[1-(3-Bromophenyl)Cyclopentanecarbonyl]Amino]-3-Methyl-8-Oxo -5-Thia-1-Azabicyclo[4.2.0]Oct-2-Ene-2-Carboxylate
CAS No.	143407-74-3
Molecular Formula	C21H22BrN3NaO4S
Molecular Weight	506.38 g/mol
Synonyms	Sodium (6R,7R)-7-[[(1-(3-Bromophenyl)cyclopentyl)carbonyl]amino]-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate; 7-[[1-(3-Bromophenyl)Cyclopentanecarbonyl]Amino]-3-Methyl-8-Oxo-5-Thia-1-Azabicyclo[4.2.0]Oct-2-Ene-2-Carboxylic Acid Sodium Salt; Cephalosporin Intermediate 143407-74-3; 3-Bromophenyl Cyclopentyl Cephalosporin Sodium Salt
EINECS	Contact for details

Quality Control

Our Sodium 7-[[1-(3-Bromophenyl)Cyclopentanecarbonyl]Amino]-3-Methyl-8-Oxo -5-Thia-1-Azabicyclo[4.2.0]Oct-2-Ene-2-Carboxylate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing including HPLC, NMR, and mass spectrometry to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications and test results is provided with each shipment. We support development and commercial projects requiring compliance with ICH guidelines and relevant pharmacopeial standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and purity. For long-term storage, consider desiccated or nitrogen-purged environments.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.