Description

Shaker Potassium Channel CAS NO 143403-88-7 is a high-purity, synthetic organic compound specifically designed for advanced biochemical and pharmacological research. This compound is a critical tool for studying ion channel function and modulation, which is fundamental to understanding neurological and cardiovascular physiology. It is primarily utilized by pharmaceutical R&D teams, academic research institutions, and biotechnology companies focused on developing novel therapeutics for channelopathies and related disorders.

Application

• Neuroscience Research: As a key reagent for electrophysiological studies (e.g., patch-clamp) to investigate the gating kinetics and pharmacology of potassium channels.
• Drug Discovery & Screening: Used in high-throughput screening (HTS) assays to identify and validate new modulators or blockers of shaker-type potassium channels.
• Cardiovascular Research: Applied in studies of cardiac action potentials and arrhythmias where potassium channels play a crucial regulatory role.
• Toxicology Studies: Employed to assess the effects of environmental toxins or new chemical entities on ion channel function and cellular excitability.
• Academic & Institutional Labs: Serves as a standard compound for teaching and fundamental research in molecular biology and cellular physiology courses.
• Biomarker Development: Potential use in developing diagnostic assays for diseases linked to potassium channel dysfunction.

Basic Information

Item	Detail
Product Name	Shaker Potassium Channel CAS NO 143403-88-7
CAS No.	143403-88-7
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Shaker K+ Channel Blocker; Potassium Channel Inhibitor 143403-88-7; Shaker Family Potassium Channel Modulator; Ion Channel Research Compound 143403-88-7; Neuroactive Potassium Channel Agent; Electrophysiology Research Chemical; Kv1 Channel Reference Standard
EINECS	Contact for details

Quality Control

Every batch of our Shaker Potassium Channel compound is manufactured under strict quality management protocols. We guarantee high purity and batch-to-batch consistency through rigorous analytical testing, including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to ensure it meets the exacting standards required for sensitive research applications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dedicated freezer. The product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature before opening to minimize condensation. For long-term storage, consider under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.