Description

Acetamide, n-(2-Ethynylphenyl)-2,2,2-Trifluoro- CAS NO 143360-93-4 is a specialized trifluoroacetamide derivative featuring a reactive ethynylphenyl group. This compound serves as a high-value building block in advanced organic synthesis, enabling the construction of complex molecular architectures. It is primarily utilized by pharmaceutical R&D and agrochemical laboratories for developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of new drug candidates, particularly in medicinal chemistry programs targeting enzyme inhibition.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, leveraging the trifluoromethyl group for enhanced bioactivity and stability.
• Material Science Research: Serves as a precursor for specialty polymers, liquid crystals, or organic electronic materials due to its conjugated ethynyl moiety.
• Chemical Biology Probes: Employed in the synthesis of molecular probes and tags for studying biological processes, where the alkyne group enables click chemistry conjugation.
• Custom Synthesis & Contract Manufacturing: Supplied to fine chemical companies for custom synthesis projects requiring high-purity, complex fluorinated intermediates.

Basic Information

Item	Detail
Product Name	Acetamide, n-(2-Ethynylphenyl)-2,2,2-Trifluoro-
CAS No.	143360-93-4
Molecular Formula	C10H6F3NO
Molecular Weight	213.16 g/mol
Synonyms	N-(2-Ethynylphenyl)-2,2,2-trifluoroacetamide; 2,2,2-Trifluoro-N-(2-ethynylphenyl)acetamide; 2-Ethynylphenyl trifluoroacetamide; Trifluoroacetic acid 2-ethynylanilide; 2-Ethynylaniline, N-trifluoroacetyl derivative; 143360-93-4; N-(2-Ethynylphenyl)trifluoroacetamide
EINECS	Contact for details

Quality Control

Our Acetamide, n-(2-Ethynylphenyl)-2,2,2-Trifluoro- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment. We support compliance with REACH and other global regulatory frameworks.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under dry conditions, such as a nitrogen or argon atmosphere, for long-term storage. Keep away from incompatible materials such as strong bases and fluorides.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.