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n-(4-Bromo-3-Chloro-2-Fluorophenyl)Acetamide CAS NO 143360-05-8
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CAS No.:143360-05-8
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
n-(4-Bromo-3-Chloro-2-Fluorophenyl)Acetamide is a high-purity halogenated aromatic acetamide intermediate of significant importance in advanced organic synthesis. This compound matters for its role as a critical building block in the development of complex molecules, particularly in the pharmaceutical and agrochemical sectors. It is primarily needed by research and development chemists and process engineers in fine chemical manufacturing for creating active pharmaceutical ingredients (APIs) and novel crop protection agents.
Application
- Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and anti-inflammatory applications.
- Agrochemical Synthesis: Serves as a core scaffold for developing new-generation herbicides and fungicides with enhanced efficacy and selectivity.
- Material Science Research: Used in the development of specialty polymers and liquid crystals where halogenated aromatic units are required for specific electronic or steric properties.
- Organic Light-Emitting Diode (OLED) Materials: Acts as a starting material for synthesizing electron-transport or host materials in OLED devices.
- Chemical Biology Probes: Utilized in medicinal chemistry for structure-activity relationship (SAR) studies and as a tagged molecule in probe development.
Basic Information
| Product Name | n-(4-Bromo-3-Chloro-2-Fluorophenyl)Acetamide |
| CAS No. | 143360-05-8 |
| Molecular Formula | C8H6BrClFNO |
| Molecular Weight | 266.50 g/mol |
| Synonyms | 4-Bromo-3-chloro-2-fluoroacetanilide; N-(4-Bromo-3-chloro-2-fluorophenyl)acetamide; 2-Fluoro-4-bromo-3-chloroacetanilide; Acetamide, N-(4-bromo-3-chloro-2-fluorophenyl)-; 1-(4-Bromo-3-chloro-2-fluorophenyl)ethan-1-one amine; 4'-Bromo-3'-chloro-2'-fluoroacetamilide; 143360-05-8; BCFA |
| EINECS | Contact for details |
Quality Control
Our n-(4-Bromo-3-Chloro-2-Fluorophenyl)Acetamide is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliable supply for your most demanding synthesis workflows.
Storage
Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed to prevent moisture absorption. Store away from incompatible materials such as strong oxidizing agents and strong bases.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Identification (IR) | Conforms to structure |
| Identification (HPLC) | Retention time matches reference standard |
| Assay (HPLC) | ≥98.0% |
| Related Substances (HPLC) | Total impurities ≤2.0% |
| Any single impurity | ≤0.5% |
| Loss on Drying | ≤0.5% |
| Residue on Ignition | ≤0.1% |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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