Description

Cyclopentanecarbonitrile, 1-(2-Chlorophenyl)- is a specialized organic nitrile building block of significant interest in advanced chemical synthesis. This compound matters for its role as a key chiral intermediate in the development of active pharmaceutical ingredients (APIs) and other high-value fine chemicals. It is primarily needed by research and development chemists, process development scientists, and manufacturers in the pharmaceutical, agrochemical, and material science industries seeking to construct complex molecular architectures.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and cardiovascular therapeutic areas.
• Agrochemical Research: Used in the development of advanced pesticides and herbicides, where the cyclopentane and nitrile functionalities contribute to biological activity.
• Ligand and Catalyst Preparation: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Monomer: Potential building block for specialty polymers and advanced organic materials with unique thermal or optical properties.
• Chemical Biology Probe Synthesis: Employed in creating molecular probes for studying enzyme function and biological pathways.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific molecule production.

Basic Information

Product Name	Cyclopentanecarbonitrile, 1-(2-Chlorophenyl)-
CAS No.	143328-15-8
Molecular Formula	C12H12ClN
Molecular Weight	205.68 g/mol
Synonyms	1-(2-Chlorophenyl)cyclopentanecarbonitrile; (2-Chlorophenyl)cyclopentyl cyanide; 1-(o-Chlorophenyl)cyclopentanecarbonitrile; 1-(2-Chlorophenyl)cyclopentane-1-carbonitrile; Cyclopentanecarbonitrile, 1-(2-chlorophenyl)-; 1-(2-Chlorophenyl)-1-cyanocyclopentane; 2-Chloro-α-(cyanocyclopentyl)benzene; α-(2-Chlorophenyl)cyclopentanecarbonitrile
EINECS	Contact for details

Quality Control

Our production of Cyclopentanecarbonitrile, 1-(2-Chlorophenyl)- adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity for sensitive synthetic applications. Each lot undergoes comprehensive analytical characterization, including chiral purity assessment via HPLC. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to minimize exposure to moisture. Store away from incompatible materials such as strong oxidizing agents, strong acids, and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.