Description

Streptococcal Group B Hemolysin CAS NO 143257-99-2 is a highly purified bacterial toxin, specifically a pore-forming cytolysin produced by *Streptococcus agalactiae* (Group B Streptococcus). This reagent is critical for research into the pathogenesis, immune response, and diagnostic detection of Group B Streptococcal infections. It is primarily utilized by research institutions, diagnostic kit manufacturers, and pharmaceutical companies engaged in vaccine development and antimicrobial discovery.

Application

• Research Reagent: Used in microbiological and immunological studies to investigate the virulence mechanisms of Group B Streptococcus (GBS).
• Diagnostic Development: Serves as a key antigen or control material in the development of immunoassays and rapid tests for GBS detection.
• Vaccine Research: Employed as a target antigen in preclinical research for the development of vaccines against streptococcal infections.
• Cytotoxicity Studies: Used in cell culture models to study host cell membrane damage and pore-forming toxin activity.
• Antibody Production: Acts as an immunogen for generating specific polyclonal or monoclonal antibodies for research and diagnostic use.
• Quality Control: Utilized as a reference standard in the quality assurance of diagnostic products targeting GBS hemolysin.

Basic Information

Product Name	Streptococcal Group B Hemolysin
CAS No.	143257-99-2
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	GBS Hemolysin; Group B Streptococcal Hemolysin; β-hemolysin (GBS); Streptococcus agalactiae Hemolysin; Cytolysin (GBS); Pore-forming toxin (GBS); Streptolysin (Group B); GBS Toxin
EINECS	Contact for details

Quality Control

Our Streptococcal Group B Hemolysin is produced under stringent conditions to ensure high biological activity and purity, suitable for critical research and diagnostic applications. Each batch is subjected to rigorous quality testing including identity confirmation, purity assessment, and activity assays. A comprehensive Certificate of Analysis (COA) detailing specific test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive). For long-term storage, consider aliquoting to avoid repeated freeze-thaw cycles. Keep containers sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (SDS-PAGE)	Conforms to reference standard
Purity (HPLC)	≥ 90%
Protein Content (BCA)	Reported on COA
Biological Activity (Hemolysis Assay)	Reported on COA
Endotoxin Level (LAL)	< 1.0 EU/µg
Solubility	Soluble in appropriate aqueous buffers

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.