Description

Trifluoro-Methanesulfonic Acid 3,4-Dihydro-Naphthalen-2-Yl Ester is a specialized triflate ester derivative, serving as a versatile and highly reactive building block in advanced organic synthesis. Its core value lies in its ability to act as a superior leaving group, facilitating efficient carbon-carbon and carbon-heteroatom bond formation under mild conditions. This compound is essential for researchers and process chemists in the pharmaceutical and agrochemical industries, particularly for constructing complex molecular architectures and developing novel active ingredients.

Application

• Pharmaceutical Intermediate: Key reagent in the synthesis of complex drug candidates, especially for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Stille, Negishi).
• Agrochemical Synthesis: Used in constructing novel herbicides, fungicides, and insecticides that require specific aromatic or heterocyclic frameworks.
• Material Science Research: Acts as a precursor for functionalized organic materials, including liquid crystals and organic semiconductors.
• Catalyst Ligand Preparation: Employed in the synthesis of sophisticated organometallic catalysts and ligands for asymmetric catalysis.
• Fine Chemical Production: Intermediate for manufacturing dyes, pigments, and other high-value specialty chemicals.

Basic Information

Product Name	Trifluoro-Methanesulfonic Acid 3,4-Dihydro-Naphthalen-2-Yl Ester
CAS No.	143139-14-4
Molecular Formula	C₁₂H₉F₃O₃S
Molecular Weight	290.26 g/mol
Synonyms	2,3-Dihydronaphthalen-2-yl trifluoromethanesulfonate; 1,2,3,4-Tetrahydronaphthalen-2-yl Triflate; 3,4-Dihydronaphthalen-2-yl Triflate; 2-Naphthalenol, 1,2,3,4-tetrahydro-, trifluoromethanesulfonate; 2-Triflyloxy-1,2,3,4-tetrahydronaphthalene; Trifluoromethanesulfonic Acid 1,2,3,4-Tetrahydro-2-naphthyl Ester; 2-(Trifluoromethanesulfonyloxy)-1,2,3,4-tetrahydronaphthalene
EINECS	Contact for details

Quality Control

Our Trifluoro-Methanesulfonic Acid 3,4-Dihydro-Naphthalen-2-Yl Ester is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and process-scale applications. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing purity, identity, and impurity profiles. Our quality system is designed to meet the stringent requirements of cGMP and ISO standards for advanced chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.