Description

Mannose-Binding Protein A (MBP-A) is a recombinant protein engineered for high-affinity binding to mannose and related carbohydrate structures. This specificity makes it a critical tool for the isolation, purification, and study of glycoproteins and pathogens in life science research and diagnostic development. It is essential for researchers and manufacturers in the biopharmaceutical, immunology, and virology sectors who require reliable, high-purity ligands for lectin-affinity chromatography and assay development.

Application

• Lectin-Affinity Chromatography: Key ligand for purifying mannose-containing glycoproteins, antibodies (e.g., IgG), and viruses.
• Diagnostic Assay Development: Used as a capture or detection reagent in ELISA, lateral flow assays, and biosensors for pathogen detection.
• Vaccine Research: Employed in studying host-pathogen interactions and purifying viral antigens for vaccine candidates.
• Glycobiology Research: Essential for analyzing protein glycosylation patterns, studying carbohydrate-protein interactions, and characterizing glycoconjugates.
• Biopharmaceutical Downstream Processing: Facilitates the purification of therapeutic proteins and monoclonal antibodies produced in mammalian cell cultures.
• Microbial Detection: Binds to surface mannans on yeast (e.g., Candida albicans) and other microbes for isolation and identification.

Basic Information

Product Name	Mannose-Binding Protein A
CAS No.	143107-68-0
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	MBP-A; Mannan-Binding Protein A; Recombinant Mannose-Binding Protein; MBP Lectin; Carbohydrate-Binding Protein A; Lectin Affinity Ligand; Mannose-Specific Lectin
EINECS	Contact for details

Quality Control

Our Mannose-Binding Protein A is produced under stringent quality management systems. Each batch undergoes rigorous analytical testing, including purity assessment by SDS-PAGE and HPLC, functional activity testing, and endotoxin level verification. A comprehensive Certificate of Analysis (COA) documenting identity, purity, biological activity, and safety parameters is provided with every shipment to ensure compliance with research and development standards.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store lyophilized material at -20°C or below. Reconstituted protein solutions should be aliquoted and stored at -70°C to -80°C to avoid repeated freeze-thaw cycles. The product is hygroscopic (moisture-sensitive); ensure containers are sealed tightly after use.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (SDS-PAGE)	Single band corresponding to expected molecular weight
Purity (HPLC)	≥ 95%
Protein Content (UV)	≥ 90%
Biological Activity (Binding Assay)	Conforms to reference standard
Endotoxin (LAL)	< 1.0 EU/μg
Solubility	Soluble in aqueous buffers

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.