Description

(1R,2S)-Fluorocyclopropylamine Tosylate is a high-value, chiral fluorinated building block essential for modern pharmaceutical and agrochemical synthesis. Its unique cyclopropylamine scaffold, combined with fluorine substitution, enables the precise modulation of biological activity, metabolic stability, and physicochemical properties in target molecules. This compound is primarily sought after by research and development chemists in the pharmaceutical industry for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in antiviral, antibacterial, and central nervous system (CNS) drug discovery programs.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the development of novel antiviral and antibacterial agents.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides with enhanced efficacy and environmental profile.
• Chemical Biology & Proteomics: Serves as a versatile handle for the synthesis of activity-based probes and molecular tools.
• Material Science Research: Investigated as a monomer or precursor for specialty polymers with unique properties.
• Asymmetric Catalysis: Employed as a ligand precursor or chiral auxiliary in stereoselective synthesis.
• Peptidomimetics: Incorporated into peptide analogs to improve stability and bioavailability.

Basic Information

Product Name	(1R,2S)-Fluorocyclopropylamine Tosylate
CAS No.	143062-84-4
Molecular Formula	C11H16FNO3S
Molecular Weight	261.31 g/mol
Synonyms	(1R,2S)-1-Amino-2-fluorocyclopropane p-toluenesulfonate; (1R,2S)-2-Fluorocyclopropanamine 4-methylbenzenesulfonate; trans-1-Amino-2-fluorocyclopropane tosylate; (1R,2S)-1-Amino-2-fluorocyclopropane tosylate salt; Fluorocyclopropylamine Tosylate; FCAT; (1R,2S)-FCAT; (1R,2S)-1-Amino-2-fluorocyclopropane Tosic Acid Salt
EINECS	Contact for details

Quality Control

Our (1R,2S)-Fluorocyclopropylamine Tosylate is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity, suitable for demanding research and scale-up applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing chiral purity, chemical purity, and impurity profiles. We adhere to cGMP principles where applicable, and our quality protocols are designed to meet the stringent requirements of pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.