Description

Long R3 Igf-I Recombinant Analog is a high-purity, engineered variant of Insulin-like Growth Factor-I (IGF-I) designed for enhanced stability and performance in cell culture applications. This analog is critical for researchers and manufacturers requiring a potent, long-acting mitogen to support the growth and differentiation of a wide range of cell types. It is an essential reagent for advanced life science research, biopharmaceutical development, and specialized cell culture processes, particularly where serum-free or defined media conditions are necessary.

Application

• Serum-Free Cell Culture Media: A key growth factor component for the proliferation of mammalian cells, including hybridomas, CHO cells, and stem cells, under defined conditions.
• Stem Cell Research & Differentiation: Used to promote the expansion and direct the differentiation of embryonic and adult stem cells into various lineages.
• Biopharmaceutical Production: Enhances cell density and viability in bioreactors for the production of monoclonal antibodies, vaccines, and recombinant proteins.
• Tissue Engineering: Supports the in vitro growth and maintenance of engineered tissues and 3D cell cultures.
• Mechanistic Biological Studies: Employed in research to investigate the IGF-I signaling pathway, its role in metabolism, growth, and oncogenesis.
• Specialized Diagnostic Development: Serves as a critical raw material or standard in the development of immunoassays and diagnostic kits.

Basic Information

Product Name	Long R3 Igf-I Recombinant Analog
CAS No.	143045-27-6
Molecular Formula	C~660~H~1026~N~184~O~196~S~8~
Molecular Weight	~15.1 kDa
Synonyms	Long R3 IGF-I; Long R3IGF-I; IGF-I Long R3; Insulin-like Growth Factor I Long R3; Long R3 Insulin-like Growth Factor-I; Recombinant Long R3 IGF-I; LR3-IGF-1; IGF-1 LR3; IGF1 Long Arg3; DES(1-3)IGF-I with N-terminal extension; CAS 143045-27-6
EINECS	Contact for details

Quality Control

Our Long R3 Igf-I Recombinant Analog is manufactured under strict quality systems. Each batch is subjected to a comprehensive battery of analytical tests, including HPLC for purity, mass spectrometry for identity confirmation, and bioactivity assays to ensure functional potency. Certificates of Analysis (COA) detailing all specifications and test results are provided to guarantee traceability, consistency, and compliance with rigorous research-grade standards.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store lyophilized powder at -20°C or below. Reconstituted solutions should be aliquoted and stored at -20°C to -80°C to avoid repeated freeze-thaw cycles. The product is hygroscopic (moisture-sensitive); ensure the vial is at room temperature before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Biological Activity (Cell-based assay)	Fully active
Endotoxin (LAL)	< 1.0 EU/µg
Moisture Content (KF)	< 5.0 %
Solubility	Soluble in water or dilute acetic acid

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.