Description

Factor Ix-Factor X-Binding Protein is a specialized recombinant protein that plays a critical role in the regulation of the blood coagulation cascade. This high-purity biological reagent is essential for research and development in hemostasis and thrombosis studies. It is primarily utilized by pharmaceutical R&D teams, diagnostic manufacturers, and academic research institutions focused on cardiovascular biology and coagulation factor pathways.

Application

• Biochemical Research: Used as a key reagent in in vitro studies to investigate the intrinsic pathway of blood coagulation and the regulatory mechanisms involving Factor IXa and Factor Xa.
• Diagnostic Development: Serves as a critical component in the development and calibration of clinical diagnostic assays for measuring coagulation factor activity and inhibitor presence.
• Pharmaceutical Screening: Employed in high-throughput screening (HTS) platforms to identify and evaluate novel anticoagulant or procoagulant drug candidates.
• Reference Standard: Acts as a purified reference material for quality control and standardization in the production of related therapeutic proteins or diagnostic kits.
• Mechanistic Studies: Facilitates detailed structure-function analysis to understand protein-protein interactions within the coagulation cascade.

Basic Information

Product Name	Factor Ix-Factor X-Binding Protein
CAS No.	143012-00-4
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Factor IX/X-Binding Protein; FIX/X-BP; Coagulation Factor IX and X Binding Protein; Recombinant FIX/X-Binding Protein; Blood Coagulation Factor Regulator; FXBP; Anticoagulant Protein; Gla-Domain Binding Protein
EINECS	Contact for details

Quality Control

Our Factor Ix-Factor X-Binding Protein is manufactured under stringent conditions to ensure high batch-to-batch consistency and biological activity. Each lot undergoes comprehensive analytical testing, including purity assessment by SDS-PAGE and HPLC, functional activity assays, and endotoxin level verification. Certificates of Analysis (COA) documenting identity, purity, potency, and safety parameters are available upon request to support your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below for long-term stability. This product is hygroscopic (moisture-sensitive); allow the vial to equilibrate to room temperature in a dry environment before opening to prevent condensation. For short-term use, aliquoting is recommended to avoid repeated freeze-thaw cycles.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (SDS-PAGE)	Single band corresponding to expected molecular weight
Purity (HPLC)	≥ 95%
Biological Activity (Assay)	Contact for details
Endotoxin (LAL)	< 1.0 EU/μg
Protein Content (UV)	Contact for details
Solubility	Soluble in appropriate aqueous buffers

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.