Description

3-(4'-(Ethylene-N,N,n-Trimethylamino)Phenyl)-2-Isothiocyanate is a specialized organic compound featuring a reactive isothiocyanate group linked to a quaternary ammonium-substituted phenyl ring. This unique bifunctional structure makes it a valuable intermediate for synthesizing advanced materials and bioactive molecules. It is primarily sought by researchers and manufacturers in the pharmaceutical, agrochemical, and specialty polymer industries for applications requiring targeted conjugation and modification.

Application

• Pharmaceutical Intermediate: Used in the synthesis of novel drug candidates, particularly for creating targeted conjugates or prodrugs.
• Bioconjugation Reagent: Acts as a linker for attaching fluorescent dyes, peptides, or other molecules to proteins, antibodies, or nanoparticles for diagnostic and research applications.
• Agrochemical Synthesis: Serves as a key building block in the development of new pesticides or herbicides with specific modes of action.
• Polymer Modification: Employed to introduce cationic or reactive sites into polymer chains to alter surface properties, adhesion, or biocompatibility.
• Material Science Research: Utilized in the creation of functionalized surfaces, coatings, and advanced composite materials.
• Cross-linking Agent: Facilitates the formation of covalent bonds between molecules in hydrogel formation or polymer network development.

Basic Information

Product Name	3-(4'-(Ethylene-N,N,n-Trimethylamino)Phenyl)-2-Isothiocyanate
CAS No.	142937-20-0
Molecular Formula	C14H19N3S+ • X- (Typically supplied as a salt, e.g., iodide or chloride)
Molecular Weight	Contact for details (varies by counterion)
Synonyms	2-Isothiocyanato-3-[4'-(trimethylammonioethyl)phenyl]propionate (inner salt); 3-(4'-(2-Trimethylammonioethyl)phenyl)-2-isothiocyanate; N,N,N-Trimethyl-2-[4-(2-isothiocyanato-1-carboxyethyl)phenyl]ethanaminium; (2-Isothiocyanato-3-(4-(2-(trimethylammonio)ethyl)phenyl)propanoate); Quaternary ammonium isothiocyanate derivative; Reactive cationic isothiocyanate.
EINECS	Contact for details

Quality Control

Our production of 3-(4'-(Ethylene-N,N,n-Trimethylamino)Phenyl)-2-Isothiocyanate adheres to stringent in-process controls to ensure batch-to-batch consistency and high purity. Each lot is analyzed using advanced techniques including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment, supporting research and cGMP-grade applications where required.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label or COA. This compound is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and reactivity. Keep container tightly sealed in a desiccated environment after opening.

Specification

Item	Specification
Appearance	Off-white to light yellow powder or crystalline solid
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95% (Standard Grade)
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.