Description

Boc-5-Methyl-Dl-Tryptophan CAS NO 142847-21-0 is a protected derivative of the non-natural amino acid 5-methyltryptophan, featuring a tert-butoxycarbonyl (Boc) group on the amine functionality. This compound is a crucial building block in the synthesis of complex peptides and peptidomimetics, offering enhanced stability and solubility for solid-phase peptide synthesis (SPPS) protocols. It is primarily utilized by research institutions and pharmaceutical companies engaged in medicinal chemistry, drug discovery, and the development of novel bioactive compounds.

Application

• Peptide Synthesis Intermediate: A key protected amino acid for the stepwise construction of custom peptides in both research and process development.
• Medicinal Chemistry Research: Used in the design and synthesis of novel drug candidates, particularly those targeting neurological pathways or protein-protein interactions.
• Bioconjugation & Probe Development: Serves as a precursor for creating fluorescent or affinity-labeled probes for biochemical and cellular studies.
• Pharmaceutical Reference Standard: Employed as a high-purity analytical standard for quality control and method development in API manufacturing.
• Academic & Institutional Research: Fundamental research tool in biochemistry and organic chemistry laboratories for studying protein structure and function.

Basic Information

Product Name	Boc-5-Methyl-Dl-Tryptophan
CAS No.	142847-21-0
Molecular Formula	C₁₉H₂₄N₂O₄
Molecular Weight	344.41 g/mol
Synonyms	N-(tert-Butoxycarbonyl)-5-methyl-DL-tryptophan; Boc-5-Me-DL-Trp-OH; 2-[[(2-Methyl-1H-indol-3-yl)methyl]-(tert-butoxycarbonyl)amino]acetic acid; 5-Methyl-DL-tryptophan, N-BOC-; tert-Butyl (1-((5-methyl-1H-indol-3-yl)methyl)-2-carboxyethyl)carbamate; N-Boc-5-methyltryptophan; DL-5-Methyltryptophan, N-Boc derivative
EINECS	Contact for details

Quality Control

Our Boc-5-Methyl-Dl-Tryptophan is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and chiral analysis to verify the DL-mixture. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, ensuring compliance with research and development grade specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.