Description

Neuropeptide Y, N(Epsilon,7)-Biotinyl-Lys(7)- is a biotinylated derivative of the potent neuropeptide Y (NPY), designed for advanced research applications. This modified peptide is crucial for studying NPY receptor interactions, signal transduction pathways, and protein-protein binding events through high-affinity biotin-streptavidin capture systems. It is an essential tool for researchers and developers in neuroscience, metabolic disorder research, and pharmaceutical discovery, enabling precise detection and isolation of NPY-binding complexes.

Application

• Biochemical Research: Used as a labeled ligand in receptor binding assays and affinity studies for NPY receptor subtypes (Y1, Y2, Y4, Y5, Y6).
• Diagnostic Development: Serves as a critical component in the development of ELISA, Western blot, and other immunoassay platforms for NPY detection.
• Pull-Down Assays: Facilitates the isolation and identification of NPY-interacting proteins and receptor complexes using streptavidin-coated beads or surfaces.
• Cell Signaling Studies: Employed to investigate NPY-mediated signaling cascades in neuronal, cardiovascular, and adipose tissues.
• Drug Discovery: Acts as a key reagent in high-throughput screening (HTS) campaigns to identify novel NPY receptor agonists or antagonists.
• Molecular Imaging: Can be conjugated with fluorescent tags or other probes for cellular localization and trafficking studies of NPY pathways.

Basic Information

Product Name	Neuropeptide Y, N(Epsilon,7)-Biotinyl-Lys(7)-
CAS No.	142724-98-9
Molecular Formula	C192H290N56O57S
Molecular Weight	4252.7 g/mol
Synonyms	Biotinylated Neuropeptide Y; Biotin-NPY; NPY-Biotin; [Lys7(Biotin)]Neuropeptide Y; Neuropeptide Y (biotinylated); NPY (Biotin); Biotinyl-Lys7-Neuropeptide Y; Biotinylated NPY Fragment
EINECS	Contact for details

Quality Control

Our Neuropeptide Y, N(Epsilon,7)-Biotinyl-Lys(7)- is manufactured under strict quality systems to ensure batch-to-batch consistency and high biological activity. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and performance in standard assays. We adhere to GMP principles for research-grade bioactive peptides, ensuring reliability for your critical experiments.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a desiccated environment. This product is hygroscopic (moisture-sensitive). For long-term storage, solutions should be aliquoted to avoid repeated freeze-thaw cycles.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC & MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Peptide Content	≥ 70% (by weight)
Water Content (KF)	≤ 5.0%
Biological Activity	Confirmed by receptor binding assay

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.