Description

3-n-Boc-Aminomethylpiperidine is a high-purity, protected amine building block essential for modern organic synthesis. Its primary value lies in providing a versatile and reactive nitrogen-containing scaffold for constructing complex molecules, particularly in pharmaceutical research and development. This compound is critically needed by medicinal chemists and process development scientists for the synthesis of active pharmaceutical ingredients (APIs) and novel chemical entities.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of drug candidates, particularly those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Peptidomimetic Synthesis: Used to introduce constrained piperidine scaffolds into peptide analogs to enhance metabolic stability and bioavailability.
• Ligand and Catalyst Development: Serves as a precursor for creating chiral ligands and organocatalysts used in asymmetric synthesis.
• Combinatorial Chemistry: Employed in solid-phase and solution-phase parallel synthesis libraries for high-throughput screening.
• Agrochemical Research: Utilized as an intermediate in the development of novel crop protection agents and pesticides.
• Material Science: Acts as a monomer or cross-linking agent in the development of specialty polymers and functional materials.

Basic Information

Product Name	3-n-Boc-Aminomethylpiperidine
CAS No.	142643-29-6
Molecular Formula	C11H22N2O2
Molecular Weight	214.31 g/mol
Synonyms	1-Boc-3-(Aminomethyl)piperidine; tert-Butyl 3-(Aminomethyl)piperidine-1-carboxylate; 3-(Aminomethyl)piperidine-1-carboxylic Acid tert-Butyl Ester; 1-N-Boc-3-(Aminomethyl)piperidine; N-Boc-3-piperidinemethylamine; 3-(Aminomethyl)-1-N-Boc-piperidine; 3-Piperidinemethylamine, N-Boc-; 1-(tert-Butoxycarbonyl)-3-(aminomethyl)piperidine
EINECS	Contact for details

Quality Control

Our 3-n-Boc-Aminomethylpiperidine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC, to ensure high chemical purity and identity. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to guarantee traceability and compliance with your research or production standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.