Description

9,11-Dicis-12-Fluororhodopsin is a specialized, fluorinated derivative of the visual pigment rhodopsin, designed for advanced photochemical and biochemical research. This compound matters for its unique spectral properties and structural modifications, which enable precise studies in photobiology, vision science, and the development of novel optogenetic tools. It is essential for researchers and developers in the pharmaceutical, biotechnology, and advanced materials sectors who require high-purity, well-characterized probes for investigating G-protein coupled receptor (GPCR) mechanisms and light-sensitive processes.

Application

• Photobiology Research: As a model compound for studying the photoisomerization mechanisms of retinal proteins and the impact of fluorine substitution on chromophore behavior.
• Vision Science Studies: Used in spectroscopic and biochemical assays to investigate the structure-function relationship in modified visual pigments and related GPCRs.
• Optogenetics Tool Development: Serves as a precursor or template for engineering novel, light-sensitive proteins with tailored spectral sensitivities for controlling cellular activity.
• Biochemical Reference Standard: Acts as a high-purity analytical standard for the identification and quantification of related retinoid and opsin derivatives in complex matrices.
• Advanced Material Synthesis: A key intermediate in the research and development of bio-inspired, light-responsive materials and molecular switches.
• Pharmaceutical R&D: Utilized in drug discovery programs targeting retinal diseases and disorders related to visual signal transduction pathways.

Basic Information

Product Name	9,11-Dicis-12-Fluororhodopsin
CAS No.	142632-01-7
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	12-Fluoro-9,11-dicis-rhodopsin; Fluororhodopsin derivative; 9,11-Dicis-12-F-retinal-opsin complex; Modified rhodopsin fluorophore; 12-Fluororetinal-rhodopsin; Vision pigment analog; Light-sensitive GPCR probe; 9,11-Dicis-12-F-opsin
EINECS	Contact for details

Quality Control

Our 9,11-Dicis-12-Fluororhodopsin is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity, suitable for sensitive research applications. Each lot is characterized using advanced analytical techniques including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and related substance profiles is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to minimize oxidation and degradation. The container should be kept in a dry environment to protect this hygroscopic (moisture-sensitive) material. Allow the sealed container to equilibrate to room temperature before opening to prevent condensation.

Specification

Item	Specification
Appearance	Orange to red solid or film
Identification (HPLC)	Conforms to reference standard
Identification (UV-Vis)	Characteristic absorption spectrum
Purity (HPLC)	≥ 95% (Area %)
Related Substances (HPLC)	Total impurities ≤ 5.0%
Water Content (KF)	≤ 1.0%
Solvent Residues (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.