Description

2-Nitro-4-(Trifluoromethoxy)Benzonitrile is a high-value, multi-functional aromatic intermediate featuring both nitro and trifluoromethoxy substituents. This compound is critical for synthesizing advanced molecules where electron-withdrawing groups and fluorine atoms are required to modulate biological activity, stability, and physicochemical properties. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of drug candidates, particularly in areas targeting central nervous system (CNS) disorders, inflammation, and oncology, where the trifluoromethoxy group enhances metabolic stability and membrane permeability.
• Agrochemical Active Ingredient Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, leveraging the nitro group for reactivity and the fluorine content for improved lipophilicity and weatherfastness.
• Material Science Research: Serves as a precursor for developing specialty polymers, liquid crystals, and organic electronic materials due to its aromatic core and polar functional groups.
• Chemical Synthesis & Custom Manufacturing: Employed as a versatile nitrile-containing substrate for further functionalization, including reduction, hydrolysis, or cyclization reactions in fine chemical production.

Basic Information

Product Name	2-Nitro-4-(Trifluoromethoxy)Benzonitrile
CAS No.	142494-69-7
Molecular Formula	C8H3F3N2O3
Molecular Weight	232.12 g/mol
Synonyms	4-(Trifluoromethoxy)-2-nitrobenzonitrile; 2-Nitro-4-trifluoromethoxybenzonitrile; Benzonitrile, 2-nitro-4-(trifluoromethoxy)-; 2-Nitro-α,α,α-trifluoro-p-anisonitrile
EINECS	Contact for details

Quality Control

Every batch of 2-Nitro-4-(Trifluoromethoxy)Benzonitrile is manufactured under a strict quality management system. We provide comprehensive analytical documentation to ensure traceability and compliance with your project requirements. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.