Description

(2R,5R)-(+)-Bis(Diphenylphosphino)Hexane is a high-purity, chiral bidentate phosphine ligand essential for asymmetric catalysis. Its value lies in its ability to induce high enantioselectivity in transition metal-catalyzed reactions, a critical factor for producing optically active intermediates. This compound is primarily needed by research institutions and pharmaceutical manufacturers developing novel active pharmaceutical ingredients (APIs) and fine chemicals.

Application

• As a chiral ligand in asymmetric hydrogenation reactions for the synthesis of enantiomerically pure amino acids and pharmaceutical intermediates.
• Catalyst component in asymmetric cross-coupling reactions, such as Suzuki-Miyaura and Heck reactions, to form chiral biaryl compounds.
• Key reagent in the development of novel organometallic catalysts for academic and industrial research in stereoselective synthesis.
• Used in the preparation of chiral metal complexes for studying reaction mechanisms and catalyst design.
• Employed in the synthesis of specialty chemicals and agrochemicals where high optical purity is required.

Basic Information

Product Name	(2R,5R)-(+)-Bis(Diphenylphosphino)Hexane
CAS No.	142494-67-5
Molecular Formula	C30H32P2
Molecular Weight	454.53 g/mol
Synonyms	(2R,5R)-1,2-Bis(diphenylphosphino)hexane; (R,R)-BDPH; (2R,5R)-BDPH; (R,R)-1,2-Bis(diphenylphosphino)hexane; (+)-(R,R)-1,2-Bis(diphenylphosphino)hexane; (R,R)-(-)-1,2-Bis(diphenylphosphino)hexane; ChiraPhos; (2R,5R)-Hexaphos
EINECS	Contact for details

Quality Control

Our (2R,5R)-(+)-Bis(Diphenylphosphino)Hexane is manufactured under strict quality systems to ensure batch-to-batch consistency and high chiral purity. Each lot is characterized by advanced analytical techniques including chiral HPLC, 31P NMR, and 1H NMR to confirm identity, enantiomeric excess, and chemical purity. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (argon or nitrogen) at 2-8°C to prevent oxidation and degradation. The container should be kept in a cool, dry, and well-ventilated area, away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (ee)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.