Description

n-Methyl-n-Methoxydifluoroacetamide CAS NO 142492-01-1 is a specialized fluorinated acetamide derivative, valued for its role as a key building block in advanced chemical synthesis. Its unique difluoroacetamide structure makes it a critical intermediate for introducing fluorinated motifs into target molecules, enhancing their biological activity and metabolic stability. This compound is primarily sought by research and development teams in the pharmaceutical and agrochemical industries for the creation of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of fluorinated drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where fluorine atoms improve efficacy and environmental profile.
• Material Science Research: Serves as a precursor for fluorinated polymers or specialty chemicals with unique surface properties.
• Organic Synthesis Building Block: Employed in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization.
• Fluorine Chemistry Reagent: Utilized in academic and industrial R&D labs exploring new fluorination methodologies and compound libraries.

Basic Information

Product Name	n-Methyl-n-Methoxydifluoroacetamide
CAS No.	142492-01-1
Molecular Formula	C5H9F2NO2
Molecular Weight	153.13 g/mol
Synonyms	N-Methoxy-N-methyl-2,2-difluoroacetamide; 2,2-Difluoro-N-methoxy-N-methylacetamide; Difluoroacetic acid N-methoxy-N-methylamide; N-Methoxy-N-methyldifluoroacetamide; N-Methyl-N-methoxy-2,2-difluoroacetamide; Weinreb amide of difluoroacetic acid; N-Methoxy-N-methyl-α,α-difluoroacetamide
EINECS	Contact for details

Quality Control

Our n-Methyl-n-Methoxydifluoroacetamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials such as strong acids, bases, and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.