Description

Bicyclo[2.2.1]Heptan-7-One, 2,3-Difluoro-, (1R,2R,3S,4S)-Rel- (9Ci) is a high-purity, stereochemically defined fluorinated bicyclic ketone, serving as a critical chiral building block in advanced organic synthesis. Its unique, rigid molecular framework and fluorine substitution pattern make it an invaluable intermediate for constructing complex molecules with precise three-dimensional architecture. This compound is essential for research and development in the pharmaceutical and agrochemical industries, where it is used to create novel active ingredients with enhanced properties. The product is supplied under strict quality control, with CAS number 142473-47-0.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the development of new active pharmaceutical ingredients (APIs), particularly in antiviral, anticancer, and central nervous system (CNS) drug candidates.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the fluorine atoms and rigid structure can improve biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis to control stereoselectivity.
• Material Science Research: Investigated as a monomer or additive for creating specialty polymers with unique thermal, optical, or surface properties.
• Fluorine Chemistry Studies: An important compound for academic and industrial research focused on the synthesis and behavior of fluorinated organic molecules.
• Fine Chemical Production: Employed in the multi-step synthesis of complex flavors, fragrances, and other high-value specialty chemicals.

Basic Information

Product Name	Bicyclo[2.2.1]Heptan-7-One, 2,3-Difluoro-, (1R,2R,3S,4S)-Rel- (9Ci)
CAS No.	142473-47-0
Molecular Formula	C7H8F2O
Molecular Weight	146.14 g/mol
Synonyms	(1R,2R,3S,4S)-2,3-Difluorobicyclo[2.2.1]heptan-7-one; rel-(1R,2R,3S,4S)-2,3-Difluoronorbornan-7-one; 2,3-Difluoronorbornan-7-one (specific isomer); exo,exo-2,3-Difluorobicyclo[2.2.1]heptan-7-one; Fluorinated Norbornanone Derivative; Bicyclo[2.2.1]heptan-7-one, 2,3-difluoro-, (1R,2R,3S,4S)-rel-; 142473-47-0
EINECS	Contact for details

Quality Control

Every batch of Bicyclo[2.2.1]Heptan-7-One, 2,3-Difluoro-, (1R,2R,3S,4S)-Rel- (9Ci) is manufactured and analyzed under a strict quality management system. Our products undergo rigorous quality testing, including chiral purity analysis and impurity profiling, to ensure compliance with the highest industry standards for research and process chemistry. A comprehensive Certificate of Analysis (COA) detailing identity, purity (HPLC/GC), chiral excess, and specific tests is provided with each shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline solid or powder
Identification (IR)	Conforms to reference spectrum
Purity (HPLC/GC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee (enantiomeric excess)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.