Description

Catestatin CAS NO 142211-96-9 is a bioactive peptide fragment derived from chromogranin A, playing a significant role in cardiovascular and autonomic nervous system regulation. Its primary value lies in its potent inhibitory activity against catecholamine release, making it a critical research tool for studying hypertension, stress responses, and neuroendocrine signaling pathways. This compound is essential for researchers and developers in the pharmaceutical, biotechnology, and life science sectors focused on cardiovascular disease research, drug discovery, and diagnostic assay development.

Application

• Biomedical Research: Used as a reference standard and active agent in studies investigating the regulation of blood pressure, autonomic function, and adrenal medulla activity.
• Drug Discovery & Development: Serves as a lead compound or pharmacological tool for screening and developing novel therapeutics targeting hypertensive disorders and sympathetic nervous system dysregulation.
• In Vitro Diagnostics (IVD): Employed in the development and calibration of immunoassays (e.g., ELISA) to measure chromogranin A or related peptides in clinical samples.
• Neuroendocrine Studies: Applied in cellular and molecular biology research to explore the mechanisms of peptide hormone secretion and neuronal communication.
• Academic & Institutional Research: A key reagent for universities and research institutes conducting fundamental studies in physiology, pharmacology, and endocrinology.

Basic Information

Product Name	Catestatin
CAS No.	142211-96-9
Molecular Formula	C152H246N44O39S
Molecular Weight	~3440.9 g/mol
Synonyms	Human Chromogranin A (352-372); CgA(352-372); Chromogranin A Peptide (hCgA352-372); Catestatin (human); Bovine Chromogranin A (344-364) (bCgA344-364); CST; Cateslytin precursor; Parastatin related peptide
EINECS	Contact for details

Quality Control

Our Catestatin is produced and handled under stringent quality management protocols to ensure batch-to-batch consistency and reliability for critical research applications. Each lot is subjected to comprehensive analytical testing, including HPLC for purity verification and mass spectrometry for identity confirmation. A detailed Certificate of Analysis (COA), providing full characterization data, is supplied with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake. For long-term storage, keep desiccated at -20°C.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC & MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80% (by weight)
Amino Acid Composition	Conforms to theoretical sequence
Water Content (KF)	≤ 5.0%
Solubility	Soluble in water or dilute acetic acid

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.