Description

n-(2-Hydroxy-1R-Methylethyl)-Hexadecanamide is a chiral, hydroxylated fatty acid amide derivative with a defined stereochemistry. This compound is valued for its role as a versatile synthetic intermediate and functional additive, offering a unique combination of lipophilic character and reactive hydroxyl functionality. It is primarily utilized by manufacturers in the pharmaceutical, cosmetic, and specialty chemical industries for applications requiring chiral purity and surface-active properties.

Application

• Pharmaceutical Intermediate: Used in the synthesis of chiral active pharmaceutical ingredients (APIs) and prodrugs, particularly those targeting lipid metabolism or requiring specific stereochemistry.
• Cosmetic & Personal Care Formulations: Acts as a non-ionic emulsifier, skin-conditioning agent, and viscosity modifier in creams, lotions, and serums.
• Specialty Surfactant: Serves as a building block for synthesizing novel, biodegradable surfactants with low irritation potential.
• Lubricant & Metalworking Additive: Employed as a friction modifier or corrosion inhibitor in specialty lubricant formulations.
• Biochemical Research: Used as a standard or reagent in lipidomics research and studies involving cell membrane interactions.
• Polymer Modification: Functions as a chain extender or cross-linking agent in the production of polyurethanes and other specialty polymers.

Basic Information

Product Name	n-(2-Hydroxy-1R-Methylethyl)-Hexadecanamide
CAS No.	142128-47-0
Molecular Formula	C19H39NO2
Molecular Weight	313.52 g/mol
Synonyms	Hexadecanamide, N-(2-hydroxy-1-methylethyl)-, (R)-; (R)-N-(2-Hydroxy-1-methylethyl)palmitamide; Palmitoyl Ethanolamide Derivative; (R)-2-Hydroxypropyl Palmitamide; N-(2-Hydroxypropyl)hexadecanamide; Ceramide-like Synthetic Lipid; 1R,2S Stereoisomer (if applicable).
EINECS	Contact for details

Quality Control

Our n-(2-Hydroxy-1R-Methylethyl)-Hexadecanamide is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing chiral purity, assay, and impurity profiles are provided with every shipment. We can support development projects requiring compliance with ICH guidelines or current Good Manufacturing Practice (cGMP) standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); the container must be kept tightly sealed to prevent absorption of atmospheric moisture, which can affect stability and performance.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% (R-isomer)
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.