Description

Boc-D-Val-Nitrile is a high-purity, protected amino acid derivative essential for advanced organic synthesis. This compound serves as a critical chiral building block, enabling the precise construction of complex peptide and peptidomimetic structures. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel therapeutic agents and fine chemical intermediates.

Application

• Peptide Synthesis: A key chiral intermediate for the solid-phase and solution-phase synthesis of custom peptides and peptide libraries.
• Pharmaceutical Research: Used in the research and development of active pharmaceutical ingredients (APIs), particularly for constructing specific amino acid sequences.
• Protease Inhibitor Development: Acts as a precursor in the synthesis of protease inhibitors and other enzyme-targeting drug candidates.
• Bioconjugation: Employed in the preparation of labeled peptides or peptide-drug conjugates for diagnostic and therapeutic applications.
• Chemical Biology: Serves as a tool compound for studying protein-protein interactions and enzyme mechanisms.
• Fine Chemical Intermediate: Used in the multi-step synthesis of complex organic molecules requiring the D-valine configuration.

Basic Information

Product Name	Boc-D-Val-Nitrile
CAS No.	142055-86-5
Molecular Formula	C₁₁H₂₀N₂O₂
Molecular Weight	212.29 g/mol
Synonyms	tert-Butyl (2R)-2-cyano-3-methylbutanoate; (R)-2-((tert-Butoxycarbonyl)amino)-3-methylbutanenitrile; Boc-D-valine nitrile; Boc-D-Val-CN; N-(tert-Butoxycarbonyl)-D-valine nitrile; D-Valine, N-[(1,1-dimethylethoxy)carbonyl]-, nitrile; BOC-D-VAL-CN
EINECS	Contact for details

Quality Control

Our Boc-D-Val-Nitrile is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and chiral analysis, to ensure it meets the high standards required for pharmaceutical research and development. A Certificate of Analysis (COA) detailing identity, purity, and specific test results is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.