Description

D-Valine, 3-Methyl-n-[(Phenylmethoxy)Carbonyl]-, Methyl Ester is a protected amino acid derivative of significant interest in advanced organic synthesis. This compound serves as a crucial chiral building block for the construction of complex peptides and peptidomimetics, offering precise stereochemical control. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel therapeutic agents, diagnostic tools, and specialized biochemical probes.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of peptide-based drugs and active pharmaceutical ingredients (APIs).
• Peptide Synthesis: Used in solid-phase and solution-phase peptide synthesis to introduce a modified D-valine residue with specific side-chain protection.
• Biochemical Research: Employed in the study of enzyme-substrate interactions, receptor binding, and the structure-activity relationships (SAR) of bioactive peptides.
• Proteomics & Diagnostics: Can be utilized in the synthesis of labeled peptides for mass spectrometry, imaging, and diagnostic assay development.
• Academic Research: Serves as a valuable reagent for synthetic organic chemistry studies and methodology development in universities and R&D labs.

Basic Information

Item	Detail
Product Name	D-Valine, 3-Methyl-n-[(Phenylmethoxy)Carbonyl]-, Methyl Ester
CAS No.	141970-46-9
Molecular Formula	C15H21NO4
Molecular Weight	279.33 g/mol
Synonyms	Methyl N-[(benzyloxy)carbonyl]-3-methyl-D-valinate; Z-D-Val-OMe; Cbz-D-Val-OMe; (R)-Methyl 2-((((benzyloxy)carbonyl)amino)-3-methylbutanoate; Methyl N-Cbz-3-methyl-D-valinate; D-3-Methylvaline, N-carbobenzoxy-, methyl ester; Benzyloxycarbonyl-D-valine methyl ester (3-methyl derivative); N-Carbobenzoxy-3-methyl-D-valine methyl ester
EINECS	Contact for details

Quality Control

Our D-Valine, 3-Methyl-n-[(Phenylmethoxy)Carbonyl]-, Methyl Ester is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and spectroscopic identification (NMR, IR, MS), to ensure it meets the high standards required for research and pharmaceutical applications. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.