Description

6-Bromo-2,2,3,3-tetrafluoro-1,4-benzodioxan is a high-value fluorinated heterocyclic building block, distinguished by its unique combination of bromine and fluorine substituents on a benzodioxane scaffold. This compound is essential for advanced research and development, particularly in the synthesis of complex molecules where its specific halogen pattern enables precise structural modifications and introduces desirable physicochemical properties. It is primarily sought by pharmaceutical, agrochemical, and advanced materials chemists for creating novel active ingredients, functional materials, and ligands for catalysis.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for introducing fluorine atoms to modulate bioavailability, metabolic stability, and binding affinity.
• Agrochemical Synthesis: Used in the creation of novel herbicides, fungicides, and insecticides, where the fluorinated benzodioxane structure can enhance activity and environmental profile.
• Ligand and Catalyst Development: Serves as a precursor for sophisticated ligands in transition metal catalysis, enabling new synthetic methodologies.
• Advanced Material Precursor: Employed in the synthesis of fluorinated polymers, liquid crystals, or electronic materials requiring specific dielectric properties.
• Organic Synthesis Building Block: Utilized in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and nucleophilic substitutions due to the reactive bromine substituent.

Basic Information

Product Name	6-Bromo-2,2,3,3-tetrafluoro-1,4-benzodioxan
CAS No.	141872-90-4
Molecular Formula	C8H2BrF4O2
Molecular Weight	294.99 g/mol
Synonyms	6-Bromo-2,2,3,3-tetrafluoro-1,4-benzodioxane; 1,4-Benzodioxan, 6-bromo-2,2,3,3-tetrafluoro-; 2,2,3,3-Tetrafluoro-6-bromo-1,4-benzodioxane; 6-Bromo-2,2,3,3-tetrafluoro-benzo[1,4]dioxine; Benzo[1,4]dioxin, 6-bromo-2,2,3,3-tetrafluoro-
EINECS	Contact for details

Quality Control

Our 6-Bromo-2,2,3,3-tetrafluoro-1,4-benzodioxan is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, documenting all critical quality parameters. Our quality commitment supports applications requiring high-purity intermediates for GMP and non-GMP research.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials. The container should be kept tightly sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Melting Point	Contact for details
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.