Description

Nalpha-9-Fluorenylmethoxycarbonyl-n-Benzylglycine is a specialized amino acid derivative designed for advanced peptide synthesis. This compound matters as a crucial building block for introducing the benzylglycine residue under Fmoc-protection strategies, ensuring high coupling efficiency and purity in complex peptide sequences. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of therapeutic peptides, peptidomimetics, and novel bioactive compounds. Its reliable quality is essential for reproducible results in solid-phase and solution-phase peptide synthesis.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key protected amino acid for the automated, stepwise construction of peptides using Fmoc chemistry.
• Pharmaceutical Research: Serves as a critical intermediate in the research and development of new peptide-based drugs and APIs.
• Peptidomimetic Design: Used to incorporate the benzylglycine side chain into non-natural peptide analogs to enhance stability or biological activity.
• Bioconjugation: Acts as a component for creating custom peptide tags or linkers for protein labeling and bioconjugation projects.
• Combinatorial Chemistry: Employed in libraries for high-throughput screening to discover new lead compounds with specific biological targets.
• Academic Research: Utilized in biochemistry and molecular biology laboratories for studying protein-protein interactions and enzyme substrates.

Basic Information

Product Name	Nalpha-9-Fluorenylmethoxycarbonyl-n-Benzylglycine
CAS No.	141743-13-7
Molecular Formula	C25H23NO4
Molecular Weight	401.46 g/mol
Synonyms	Fmoc-N-Bzl-Gly-OH; N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-N-(phenylmethyl)glycine; Fmoc-Benzylglycine; Fmoc-N-benzyl-glycine; Nα-Fmoc-N-benzylglycine; (2-(((9H-Fluoren-9-yl)methoxy)carbonyl)(benzyl)amino)acetic acid; N-Fmoc-N-benzylglycine; Nα-(9-Fluorenylmethoxycarbonyl)-N-benzylglycine
EINECS	Contact for details

Quality Control

Our Nalpha-9-Fluorenylmethoxycarbonyl-n-Benzylglycine is manufactured under strict quality systems to ensure it meets the high-purity standards required for sensitive peptide synthesis. Each batch is subjected to comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation. Certificates of Analysis (COA) detailing all specifications are available upon request to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Specific Rotation	Contact for details
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.