Description

1-Boc-4-Methanesulfonyloxypiperidine is a high-purity, protected piperidine derivative of significant importance in advanced organic synthesis. This compound serves as a versatile and critical building block for the construction of complex molecules, particularly in pharmaceutical research and development. It is primarily needed by medicinal chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for creating novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially those containing functionalized piperidine scaffolds.
• Medicinal Chemistry: Used in research for structure-activity relationship (SAR) studies and the development of new drug candidates targeting CNS disorders, oncology, and infectious diseases.
• Peptidomimetics Synthesis: Employed in the construction of peptidomimetics and constrained peptides where the piperidine ring mimics natural amino acid structures.
• Ligand and Catalyst Development: Serves as a starting material for creating chiral ligands, organocatalysts, and other specialty chemicals used in asymmetric synthesis.
• Agrochemical Research: Utilized in the development of novel herbicides, fungicides, and insecticides that incorporate nitrogen heterocycles.
• Custom Synthesis & Contract Manufacturing: A fundamental building block for custom synthesis projects and scale-up processes in contract research and manufacturing organizations (CROs/CMOs).

Basic Information

Product Name	1-Boc-4-Methanesulfonyloxypiperidine
CAS No.	141699-59-4
Molecular Formula	C11H21NO5S
Molecular Weight	279.35 g/mol
Synonyms	1-Boc-4-(Methylsulfonyloxy)piperidine; 4-[(tert-Butoxycarbonyl)oxy]-1-piperidinyl Methanesulfonate; tert-Butyl 4-((methylsulfonyl)oxy)piperidine-1-carboxylate; N-Boc-4-Methanesulfonyloxypiperidine; 1-(tert-Butoxycarbonyl)-4-methanesulfonyloxypiperidine; 4-Methanesulfonyloxy-1-piperidinecarboxylic Acid tert-Butyl Ester; Piperidine, 4-[(methylsulfonyl)oxy]-, 1-(1,1-dimethylethyl) ester
EINECS	Contact for details

Quality Control

Our 1-Boc-4-Methanesulfonyloxypiperidine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for research and process chemistry. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.