Description

Boc-D-Ser(Tos)-o-Bzl CAS NO 141527-79-9 is a protected, non-natural amino acid derivative specifically engineered for advanced peptide synthesis. This compound is critical for constructing complex peptide sequences with precise stereochemistry and functional group control. It is primarily utilized by pharmaceutical R&D teams, biotechnology companies, and fine chemical manufacturers engaged in the development of novel therapeutic peptides, peptidomimetics, and biochemical probes.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key building block for the controlled incorporation of D-serine derivatives into peptide chains, enabling the creation of peptides with enhanced metabolic stability and specific biological activity.
• Pharmaceutical Intermediate: Serves as a crucial intermediate in the research and development of peptide-based drugs, including hormone analogs, enzyme inhibitors, and targeted therapeutics.
• Bioconjugation and Probe Development: Used to introduce protected serine moieties into larger molecules for bioconjugation or as part of fluorescent or affinity tags for biochemical research.
• Combinatorial Chemistry Libraries: Employed in the generation of diverse peptide libraries for high-throughput screening in drug discovery programs.
• Academic and Institutional Research: Essential for fundamental studies in peptide chemistry, structural biology, and medicinal chemistry within university and government laboratories.

Basic Information

Product Name	Boc-D-Ser(Tos)-o-Bzl
CAS No.	141527-79-9
Molecular Formula	C22H27NO7S
Molecular Weight	449.52 g/mol
Synonyms	N-(tert-Butoxycarbonyl)-O-(p-toluenesulfonyl)-D-serine benzyl ester; Boc-D-Serine(Tosyl)-OBzl; Boc-D-Ser(Tos)-OBzl; (R)-2-((tert-Butoxycarbonyl)amino)-3-((4-methylphenyl)sulfonyl)oxy)propanoic acid benzyl ester; Benzyl (2R)-3-[(4-methylphenyl)sulfonyl]oxy-2-[(2-methylpropan-2-yl)oxycarbonylamino]propanoate; Boc-D-Ser(Tos)-O-Benzyl; D-Serine, N-[(1,1-dimethylethoxy)carbonyl]-, 4-methylbenzenesulfonate (ester), benzyl ester
EINECS	Contact for details

Quality Control

Our Boc-D-Ser(Tos)-o-Bzl is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity, suitable for sensitive research and development applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, chiral purity, and impurity profiles. We adhere to industry best practices, and specifications can be aligned with customer-specific requirements for advanced pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccant or inert atmosphere conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% (D-isomer)
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Single Impurity (HPLC)	≤0.5%
Total Impurities (HPLC)	≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.