Description

4,4,4-Trifluoro-3-Oxobutanenitrile Piperidine is a high-value, specialized fluorinated building block used in advanced organic synthesis. This compound is critical for introducing the trifluoroacetylacetonitrile moiety into target molecules, enabling the development of novel materials and active ingredients with enhanced properties. It is primarily sought by research and development teams in the pharmaceutical and agrochemical industries for creating new drug candidates, crop protection agents, and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly those requiring fluorinated heterocycles to modulate bioavailability and metabolic stability.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides where the trifluoromethyl group enhances biological activity and environmental persistence.
• Material Science Research: Serves as a precursor for synthesizing fluorinated ligands, polymers, and liquid crystals with unique electronic and surface properties.
• Chemical Biology Probes: Employed in the design and synthesis of fluorinated probes and tags for studying biological mechanisms and diagnostic applications.
• Organic Synthesis Building Block: Utilized in various name reactions and multi-step syntheses to construct complex, fluorinated molecular architectures.

Basic Information

Product Name	4,4,4-Trifluoro-3-Oxobutanenitrile Piperidine
CAS No.	141524-87-0
Molecular Formula	C9H11F3N2O
Molecular Weight	220.19 g/mol
Synonyms	1-(4,4,4-Trifluoro-3-oxobutanoyl)piperidine; 4,4,4-Trifluoro-1-(piperidin-1-yl)butane-1,3-dione; 4,4,4-Trifluoro-3-oxo-N-piperidin-1-ylbutanamide; 4,4,4-Trifluoroacetoacetpiperidide; TFAA Piperidine; 1-Piperidinyl 4,4,4-trifluoro-3-oxo-1-butanone; Butanenitrile, 4,4,4-trifluoro-3-oxo-, piperidine derivative
EINECS	Contact for details

Quality Control

Every batch of 4,4,4-Trifluoro-3-Oxobutanenitrile Piperidine is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure identity, purity, and consistency meet the exacting standards required for research and scale-up activities. A detailed Certificate of Analysis (COA) is supplied with each shipment, documenting key parameters such as assay (by HPLC/NMR), impurity profile, and physical characteristics.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.